Twenty of the last one hundred years of vitamin D research have involved investigations of
the brain as a target organ for this hormone. Our group was one of the first to investigate …

Radiation hazards in outer space present an enormous challenge for the biological safety of
astronauts. A deleterious effect of radiation is the production of reactive oxygen species …

Objective Our study aimed to assess the effect of a 12-month vitamin D supplementation on
cognitive function and amyloid beta (Aβ)-related biomarkers in subjects with Alzheimer's …

Despite a growing body of evidence that Vitamin D is involved in mammalian brain
functioning, there has been a lack of direct evidence about its role in the human brain. This …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Vitamin D and its metabolites have pleomorphic roles in both nervous system health and
disease. Animal models have been paramount in contributing to our knowledge and …

Accumulating data have provided evidence that 1α, 25 dihydroxyvitamin D 3 [1, 25-(OH) 2 D
3] is involved in brain function. Thus, the nuclear receptor for 1, 25-(OH) 2 D 3 has been …

Vitamin D is a fat-soluble secosteroid, traditionally considered a key regulator of bone
metabolism, calcium and phosphorous homeostasis. Its action is made possible through the …

Living beings have evolved over the past two billon years through adaptation, to an
increasing atmospheric oxygen concentration, by both taking advantage of oxygen …

It has been known for more than 20 years that vitamin D exerts marked effects on immune
and neural cells. These non-classical actions of vitamin D have recently gained a renewed …