Best practice standards for circular RNA research

AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …

Exosomal circRNA: emerging insights into cancer progression and clinical application potential

F Zhang, J Jiang, H Qian, Y Yan, W Xu - Journal of Hematology & …, 2023 - Springer
Exosomal circRNA serves a novel genetic information molecule, facilitating communication
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …

Exosome-derived circCCAR1 promotes CD8+ T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Z Hu, G Chen, Y Zhao, H Gao, L Li, Y Yin, J Jiang… - Molecular cancer, 2023 - Springer
Abstract Background Circular RNAs (circRNAs) can be encapsulated into exosomes to
participate in intercellular communication, affecting the malignant progression of a variety of …

CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities

T Ge, X Gu, R Jia, S Ge, P Chai… - Cancer …, 2022 - Wiley Online Library
Reversible, spatial, and temporal regulation of metabolic reprogramming and epigenetic
homeostasis are prominent hallmarks of carcinogenesis. Cancer cells reprogram their …

[HTML][HTML] CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer

X Meng, W Xiao, J Sun, W Li, H Yuan, T Yu, X Zhang… - Cancer Letters, 2023 - Elsevier
Bladder cancer (BCa), characterized by high invasion, metastasis, recurrence, and
chemoresistance, is one of the most prevalent urologic malignant tumors. Recent studies …

Cytoskeleton remodeling mediated by circRNA-YBX1 phase separation suppresses the metastasis of liver cancer

B Liu, H Shen, J He, B Jin, Y Tian… - Proceedings of the …, 2023 - National Acad Sciences
Metastasis, especially intrahepatic, is a major challenge for hepatocellular carcinoma (HCC)
treatment. Cytoskeleton remodeling has been identified as a vital process mediating …

Hsa_circ_0060467 promotes breast cancer liver metastasis by complexing with eIF4A3 and sponging miR-1205

Y Zeng, W Du, Z Huang, S Wu, X Ou, J Zhang… - Cell death …, 2023 - nature.com
Breast cancer (BC) is the most common cancer and the top cause of female mortality
worldwide. The prognosis for patients with breast cancer liver metastasis (BCLM) remains …

Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

CircRNAs in colorectal cancer: potential biomarkers and therapeutic targets

Y Zhang, J Luo, W Yang, WC Ye - Cell death & disease, 2023 - nature.com
Globally, colorectal cancer (CRC) is the third most prevalent cancer and the second leading
cause of cancer-related deaths. Circular RNAs (circRNAs) are single-stranded RNA with …