A number of different methods are commonly used to map the fine details of the interaction
between an antigen and an antibody. Undoubtedly the method that is now most commonly …

The binding of the tumor necrosis factor α (TNFα) to its cognate receptor initiates many
immune and inflammatory processes. The drugs, etanercept (Enbrel®), infliximab …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China,
at the end of 2019, and there are currently no specific antiviral treatments or vaccines …

Heterogeneous immunoassays such as ELISA have become indispensable in modern
bioanalysis, yet translation into point-of-care assays is hindered by their dependence on …

Cancer cells express tumour-specific antigens derived via genetic and epigenetic
alterations, which may be targeted by T-cell-mediated immune responses. However, cancer …

A novel coronavirus, designated as 2019-nCoV, emerged in Wuhan, China, at the end of
2019. As of Feb 1, 2020, at least 11,844 cases had been diagnosed in China, however …

Ebola virus causes hemorrhagic fever with a high case fatality rate for which there is no
approved therapy. Two human monoclonal antibodies, mAb100 and mAb114, in …

The interplay between inflammatory and regulatory pathways orchestrates an effective
immune response that provides protection from pathogens while limiting injury to host tissue …

Background In a subset of patients, anti tumour necrosis factor (TNF) therapeutic antibodies
are immunogenic, resulting in the formation of antidrug antibodies (ADAs). Neutralising …

Sars-CoV-2 complications include pneumonia and acute respiratory distress syndrome
(ARDS), which require intensive care unit admission. These conditions have rapidly …