Gut microbial metabolites as multi-kingdom intermediates

KA Krautkramer, J Fan, F Bäckhed - Nature Reviews Microbiology, 2021 - nature.com
The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

Recent advances in the application of metabolomics for food safety control and food quality analyses

S Li, Y Tian, P Jiang, Y Lin, X Liu… - Critical reviews in food …, 2021 - Taylor & Francis
As one of the omics fields, metabolomics has unique advantages in facilitating the
understanding of physiological and pathological activities in biology, physiology, pathology …

High‐throughput metabolomics by 1D NMR

A Vignoli, V Ghini, G Meoni, C Licari… - Angewandte Chemie …, 2019 - Wiley Online Library
Metabolomics deals with the whole ensemble of metabolites (the metabolome). As one of
the‐omic sciences, it relates to biology, physiology, pathology and medicine; but metabolites …

Gut microbiota profiling: metabolomics based approach to unravel compounds affecting human health

P Vernocchi, F Del Chierico, L Putignani - Frontiers in microbiology, 2016 - frontiersin.org
The gut microbiota is composed of a huge number of different bacteria, that produce a large
amount of compounds playing a key role in microbe selection and in the construction of a …

A review on human fecal metabolomics: Methods, applications and the human fecal metabolome database

N Karu, L Deng, M Slae, AC Guo, T Sajed, H Huynh… - Analytica chimica …, 2018 - Elsevier
Metabolomic analysis of human biospecimens had progressed quickly over the past
decade. Technological and methodological advances have led to the comprehensive …

Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults

AA Hibberd, CC Yde, ML Ziegler… - Beneficial …, 2019 - wageningenacademic.com
The gut microbiota contributes to host energy metabolism, and altered gut microbiota has
been associated with obesity-related metabolic disorders. We previously reported that a …

[HTML][HTML] APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer's disease pathophysiology

TTT Tran, S Corsini, L Kellingray, C Hegarty… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for
Alzheimer's disease (AD). Numerous studies have provided insights into the pathologic …

[HTML][HTML] Quantity and source of dietary protein influence metabolite production by gut microbiota and rectal mucosa gene expression: a randomized, parallel, double …

M Beaumont, KJ Portune, N Steuer, A Lan… - The American journal of …, 2017 - Elsevier
Background Although high-protein diets (HPDs) are frequently consumed for body-weight
control, little is known about the consequences for gut microbiota composition and metabolic …

Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn's disease

K Diederen, JV Li, GE Donachie, TG de Meij… - Scientific reports, 2020 - nature.com
A nutritional intervention, exclusive enteral nutrition (EEN) can induce remission in patients
with pediatric Crohn's disease (CD). We characterized changes in the fecal microbiota and …

Gut metabolome meets microbiome: A methodological perspective to understand the relationship between host and microbe

S Lamichhane, P Sen, AM Dickens, M Orešič… - Methods, 2018 - Elsevier
It is well established that gut microbes and their metabolic products regulate host
metabolism. The interactions between the host and its gut microbiota are highly dynamic …