The secretion profile of mesenchymal stem cells and potential applications in treating human diseases

Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …

[HTML][HTML] Reciprocal regulation of mesenchymal stem cells and immune responses

Y Wang, J Fang, B Liu, C Shao, Y Shi - Cell stem cell, 2022 - cell.com
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …

Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases

Y Shi, Y Wang, Q Li, K Liu, J Hou, C Shao… - Nature Reviews …, 2018 - nature.com
Mesenchymal stem cells (MSCs; also referred to as mesenchymal stromal cells) have
attracted much attention for their ability to regulate inflammatory processes. Their therapeutic …

Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

Y Wang, X Chen, W Cao, Y Shi - Nature immunology, 2014 - nature.com
Mesenchymal stem cells (MSCs) are multipotent stromal cells that exist in many tissues and
are capable of differentiating into several different cell types. Exogenously administered …

[HTML][HTML] Mesenchymal stromal cells: sensors and switchers of inflammation

ME Bernardo, WE Fibbe - Cell stem cell, 2013 - cell.com
In addition to their stem/progenitor properties, mesenchymal stromal cells (MSCs) possess
broad immunoregulatory properties that are being investigated for potential clinical …

Immunobiology of mesenchymal stem cells

S Ma, N Xie, W Li, B Yuan, Y Shi, Y Wang - Cell Death & Differentiation, 2014 - nature.com
Mesenchymal stem cells (MSCs) can be isolated from almost all tissues and effectively
expanded in vitro. Although their true in situ properties and biological functions remain to be …

Mesenchymal stem cells: a new trend for cell therapy

X Wei, X Yang, Z Han, F Qu, L Shao… - Acta Pharmacologica …, 2013 - nature.com
Mesenchymal stem cells (MSCs), the major stem cells for cell therapy, have been used in
the clinic for approximately 10 years. From animal models to clinical trials, MSCs have …

Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives

X Liang, Y Ding, Y Zhang, HF Tse… - Cell …, 2014 - journals.sagepub.com
Mesenchymal stem cells (MSCs) are one of a few stem cell types to be applied in clinical
practice as therapeutic agents for immunomodulation and ischemic tissue repair. In addition …

Advances in graft-versus-host disease biology and therapy

BR Blazar, WJ Murphy, M Abedi - Nature reviews immunology, 2012 - nature.com
Allogeneic haematopoietic stem cell transplantation is used to treat a variety of disorders,
but its efficacy is limited by the occurrence of graft-versus-host disease (GVHD). The past …

Same or not the same? Comparison of adipose tissue-derived versus bone marrow-derived mesenchymal stem and stromal cells

M Strioga, S Viswanathan, A Darinskas… - Stem cells and …, 2012 - liebertpub.com
Mesenchymal stem/stromal cells (MSCs) comprise a heterogeneous population of cells with
multilineage differentiation potential, the ability to modulate oxidative stress, and secrete …