RNA-binding proteins and cancer metastasis

S Wang, Z Sun, Z Lei, HT Zhang - Seminars in cancer biology, 2022 - Elsevier
RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

From conventional to precision therapy in canine mammary cancer: a comprehensive review

G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

Review of histological grading systems in veterinary medicine

G Avallone, R Rasotto, JK Chambers… - Veterinary …, 2021 - journals.sagepub.com
Tumor grading is a method to quantify the putative clinical aggressiveness of a neoplasm
based on specific histological features. A good grading system should be simple, easy to …

Overexpression of matrix metalloproteinase‐9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor …

H Dong, H Diao, Y Zhao, H Xu, S Pei, J Gao… - Cell …, 2019 - Wiley Online Library
Abstract Objectives Matrix metalloproteinase 9 (MMP‐9) has been frequently noticed in the
breast cancers. In this study, we aim to investigate the associations of MMP‐9 with the …

The novel diagnostic techniques and biomarkers of canine mammary tumors

I Kaszak, O Witkowska-Piłaszewicz, K Domrazek… - Veterinary …, 2022 - mdpi.com
Simple Summary The high rate of cancers in both humans and in animals along with their
poor overall survival pose a major challenge in medicine. Therefore, a large amount of …

Mammary glands of women, female dogs and female rats: similarities and differences to be considered in breast cancer research

T Ferreira, A Gama, F Seixas, AI Faustino-Rocha… - Veterinary …, 2023 - mdpi.com
Simple Summary Breast cancer research is frequently performed using a variety of models,
including animal models, in an attempt to provide information that can be translated into …

Associations between dog breed and clinical features of mammary epithelial neoplasia in bitches: an epidemiological study of submissions to a single diagnostic …

G Edmunds, S Beck, KU Kale, I Spasic… - Journal of Mammary …, 2023 - Springer
Mammary cancer is one of the most common neoplasms of dogs, primarily bitches. While
studies have been carried out identifying differing risk of mammary neoplasia in different dog …

Canine mammary tumors: classification, biomarkers, traditional and personalized therapies

N Nosalova, M Huniadi, Ľ Horňáková… - International Journal of …, 2024 - mdpi.com
In recent years, many studies have focused their attention on the dog as a proper animal
model for human cancer. In dogs, mammary tumors develop spontaneously, involving a …

Profiling canine mammary tumors: A potential model for studying human breast cancer

LM Gherman, P Chiroi, A Nuţu, C Bica… - The Veterinary …, 2024 - Elsevier
Despite all clinical progress recorded in the last decades, human breast cancer (HBC)
remains a major challenge worldwide both in terms of its incidence and its management …

Deciphering stromal changes between metastatic and non-metastatic canine mammary carcinomas

J Ettlin, A Bauer, L Opitz, A Malbon… - Journal of Mammary …, 2023 - Springer
Cancer-associated stroma (CAS) is widely recognized to influence development and
progression of epithelial tumours including breast cancer. Canine mammary tumours …