Mechanisms of organophosphate neurotoxicity
The canonical mechanism of organophosphate (OP) neurotoxicity is the inhibition of
acetylcholinesterase (AChE). However, multiple lines of evidence suggest that mechanisms …
acetylcholinesterase (AChE). However, multiple lines of evidence suggest that mechanisms …
Oxidative stress and mitochondrial dysfunction in organophosphate pesticide-induced neurotoxicity and its amelioration: a review
T Farkhondeh, O Mehrpour, F Forouzanfar… - … Science and Pollution …, 2020 - Springer
Organophosphorus pesticides (OPs) are widely used for controlling pests worldwide. The
inhibitory effects of these pesticides on acetylcholinesterase lead to neurotoxic damages …
inhibitory effects of these pesticides on acetylcholinesterase lead to neurotoxic damages …
Cognitive impairment and neurodegenerative diseases development associated with organophosphate pesticides exposure: a review study
M Sarailoo, S Afshari, V Asghariazar… - Neurotoxicity …, 2022 - Springer
A significant body of literature emphasizes the role of insecticide, particularly
organophosphates (OPs), as the major environmental factor in the etiology of …
organophosphates (OPs), as the major environmental factor in the etiology of …
Organophosphorus compounds and MAPK signaling pathways
T Farkhondeh, O Mehrpour, C Buhrmann… - International journal of …, 2020 - mdpi.com
The molecular signaling pathways that lead to cell survival/death after exposure to
organophosphate compounds (OPCs) are not yet fully understood. Mitogen-activated …
organophosphate compounds (OPCs) are not yet fully understood. Mitogen-activated …
N‐methyl‐d‐aspartate receptors: Structure, function, and role in organophosphorus compound poisoning
D Kolić, Z Kovarik - Biofactors, 2024 - Wiley Online Library
Acute organophosphorus compound (OP) poisoning induces symptoms of the cholinergic
crises with the occurrence of severe epileptic seizures. Seizures are induced by …
crises with the occurrence of severe epileptic seizures. Seizures are induced by …
[HTML][HTML] A microfluidic paper-based analytical device (μPAD) with smartphone readout for chlorpyrifos-oxon screening in human serum
AS Tsagkaris, D Migliorelli, L Uttl, D Filippini… - Talanta, 2021 - Elsevier
Acute intoxication incidents due to neurotoxic organophosphate (OP) insecticides are
occasionally reported, related either to suicidal attempts or occupational exposure due to the …
occasionally reported, related either to suicidal attempts or occupational exposure due to the …
Molecular mechanisms of acute organophosphate nephrotoxicity
VE Sobolev, MO Sokolova, RO Jenkins… - International Journal of …, 2022 - mdpi.com
Organophosphates (OPs) are toxic chemicals produced by an esterification process and
some other routes. They are the main components of herbicides, pesticides, and insecticides …
some other routes. They are the main components of herbicides, pesticides, and insecticides …
[HTML][HTML] Time-and region-dependent blood-brain barrier impairment in a rat model of organophosphate-induced status epilepticus
PN Bernardino, BA Hobson, SL Huddleston… - Neurobiology of …, 2023 - Elsevier
Acute organophosphate (OP) intoxication can trigger seizures that progress to status
epilepticus (SE), and survivors often develop chronic morbidities, including spontaneous …
epilepticus (SE), and survivors often develop chronic morbidities, including spontaneous …