[PDF][PDF] Role of cholesterol‐associated steatohepatitis in the development of NASH

CL Horn, AL Morales, C Savard… - Hepatology …, 2022 - Wiley Online Library
The rising prevalence of nonalcoholic fatty liver disease (NAFLD) and NAFLD‐related
cirrhosis in the United States and globally highlights the need to better understand the …

The role of cholesterol in the pathogenesis of NASH

GN Ioannou - Trends in Endocrinology & Metabolism, 2016 - cell.com
Lipotoxicity drives the development of progressive hepatic inflammation and fibrosis in a
subgroup of patients with nonalcoholic fatty liver disease (NAFLD), causing nonalcoholic …

[HTML][HTML] Plant sterols and plant stanols in the management of dyslipidaemia and prevention of cardiovascular disease

H Gylling, J Plat, S Turley, HN Ginsberg, L Ellegård… - Atherosclerosis, 2014 - Elsevier
Abstract Objective This EAS Consensus Panel critically appraised evidence relevant to the
benefit to risk relationship of functional foods with added plant sterols and/or plant stanols …

Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-alcoholic fatty liver disease (NAFLD): a systematic review and meta …

G Musso, M Cassader, F Rosina, R Gambino - Diabetologia, 2012 - Springer
Aims/hypothesis Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum
ranging from simple steatosis to non-alcoholic steatohepatitis (NASH): NAFLD causes an …

Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis

G Musso, R Gambino, M Cassader - Progress in lipid research, 2013 - Elsevier
Emerging experimental and human evidence has linked altered hepatic cholesterol
homeostasis and free cholesterol (FC) accumulation to the pathogenesis of non-alcoholic …

Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport

L Jia, JL Betters, L Yu - Annual review of physiology, 2011 - annualreviews.org
Increased blood cholesterol is an independent risk factor for atherosclerotic cardiovascular
disease. Cholesterol homeostasis in the body is controlled mainly by endogenous synthesis …

Dyslipidemia in patients with nonalcoholic fatty liver disease

H Chatrath, R Vuppalanchi… - Seminars in liver …, 2012 - thieme-connect.com
Patients with nonalcoholic fatty liver disease (NAFLD) often have dyslipidemia along with
other features of metabolic syndrome such as obesity, diabetes mellitus, and hypertension …

[HTML][HTML] Central obesity and nonalcoholic fatty liver disease risk after adjusting for body mass index

Q Pang, JY Zhang, SD Song, K Qu, XS Xu… - World Journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To investigate whether central obesity is associated with nonalcoholic fatty liver
disease (NAFLD) formation after adjusting for general obesity. METHODS: The online …

Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH [S]

GN Ioannou, S Subramanian, A Chait, WG Haigh… - Journal of lipid …, 2017 - ASBMB
We recently reported that cholesterol crystals form in hepatocyte lipid droplets (LDs) in
human and experimental nonalcoholic steatohepatitis. Herein, we assigned WT C57BL/6J …

Phytosterols, phytostanols, and lipoprotein metabolism

H Gylling, P Simonen - Nutrients, 2015 - mdpi.com
The efficacy of phytosterols and phytostanols added to foods and food supplements to
obtain significant non-pharmacologic serum and low density lipoprotein (LDL) cholesterol …