[HTML][HTML] The road to precision medicine: Eliminating the “One Size Fits All” approach in Alzheimer's disease
T Behl, I Kaur, A Sehgal, S Singh, A Albarrati… - Biomedicine & …, 2022 - Elsevier
The expeditious advancement of Alzheimer's Disease (AD) is a threat to the global
healthcare system, that is further supplemented by therapeutic failure. The prevalence of this …
healthcare system, that is further supplemented by therapeutic failure. The prevalence of this …
Exercise training for preventing dementia, mild cognitive impairment, and clinically meaningful cognitive decline: a systematic review and meta-analysis
P de Souto Barreto, L Demougeot… - The Journals of …, 2018 - academic.oup.com
Background To assess the effects of long-term exercise on the onset of dementia, mild
cognitive impairment (MCI), and other clinically meaningful cognitive decline in the elderly …
cognitive impairment (MCI), and other clinically meaningful cognitive decline in the elderly …
Methylphenidate for apathy in community-dwelling older veterans with mild Alzheimer's disease: a double-blind, randomized, placebo-controlled trial
Objective: Apathy is a common behavioral problem in Alzheimer's disease. Apathy has
profound consequences, such as functional impairment, higher service utilization, higher …
profound consequences, such as functional impairment, higher service utilization, higher …
Leisure-time physical activity and the risk of incident dementia: the mayo clinic study of aging
J Krell-Roesch, NT Feder, RO Roberts… - Journal of …, 2018 - content.iospress.com
We conducted a prospective cohort study derived from the population-based Mayo Clinic
Study of Aging. We investigated if leisure-time physical activity among individuals with mild …
Study of Aging. We investigated if leisure-time physical activity among individuals with mild …
APOEε4 and risk of Alzheimer's disease – time to move forward
The inheritance of Apolipoprotein E4 (APOEε4) brings the highest genetic risk of Alzheimer's
disease (AD), arguably the highest genetic risk in human pathology. Since the discovery of …
disease (AD), arguably the highest genetic risk in human pathology. Since the discovery of …
[HTML][HTML] Lifetime physical activity and late-life mild cognitive impairment in community-dwelling older adults
Objectives Regular physical activity throughout life is generally recommended to prevent
dementia; however, there is little evidence regarding the association between lifetime …
dementia; however, there is little evidence regarding the association between lifetime …
Does APOE genotype moderate the relationship between physical activity, brain health and dementia risk? A systematic review
Introduction For decades, researchers have tried to understand the moderating effect of
APOE ε4 carriage on the relationship between physical activity (PA), brain health and …
APOE ε4 carriage on the relationship between physical activity (PA), brain health and …
Physical activity and cognitive function: between-person and within-person associations and moderators
In the present study, we decomposed between-and within-person effects and examined
moderators of the longitudinal physical activity-cognition association. Participants (N= 1722) …
moderators of the longitudinal physical activity-cognition association. Participants (N= 1722) …
[HTML][HTML] Physical activity and beta-amyloid pathology in Alzheimer's disease: A sound mind in a sound body
Alzheimer's disease (AD) is the most common type of dementia worldwide. Since curative
treatment has not been established for AD yet and due to heavy financial and psychological …
treatment has not been established for AD yet and due to heavy financial and psychological …
Precision medicine for Alzheimer's disease prevention
CL Berkowitz, L Mosconi, O Scheyer… - The Road from …, 2020 - taylorfrancis.com
The role that genetics plays in the development of late-onset Alzheimer's disease (AD) has
been widely studied, with one study estimating genetics to account for more than 50% of the …
been widely studied, with one study estimating genetics to account for more than 50% of the …