Bladder cancer

L Dyrskjøt, DE Hansel, JA Efstathiou… - Nature Reviews …, 2023 - nature.com
Bladder cancer is a global health issue with sex differences in incidence and prognosis.
Bladder cancer has distinct molecular subtypes with multiple pathogenic pathways …

The 2022 World Health Organization classification of tumors of the urinary system and male genital organs—part B: prostate and urinary tract tumors

GJ Netto, MB Amin, DM Berney, EM Compérat, AJ Gill… - European urology, 2022 - Elsevier
Abstract The 2022 World Health Organization (WHO) classification of the urinary and male
genital tumors was recently published by the International Agency for Research on Cancer …

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment

WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman… - Nature …, 2022 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal and treatment-refractory
cancer. Molecular stratification in pancreatic cancer remains rudimentary and does not yet …

ctDNA guiding adjuvant immunotherapy in urothelial carcinoma

T Powles, ZJ Assaf, N Davarpanah, R Banchereau… - Nature, 2021 - nature.com
Minimally invasive approaches to detect residual disease after surgery are needed to
identify patients with cancer who are at risk for metastatic relapse. Circulating tumour DNA …

Advances in bladder cancer biology and therapy

L Tran, JF Xiao, N Agarwal, JE Duex… - Nature Reviews …, 2021 - nature.com
The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …

[HTML][HTML] Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

A Ravi, MD Hellmann, MB Arniella, M Holton… - Nature …, 2023 - nature.com
Abstract Anti-PD-1/PD-L1 agents have transformed the treatment landscape of advanced
non-small cell lung cancer (NSCLC). To expand our understanding of the molecular features …

Molecular map of chronic lymphocytic leukemia and its impact on outcome

BA Knisbacher, Z Lin, CK Hahn, F Nadeu… - Nature …, 2022 - nature.com
Recent advances in cancer characterization have consistently revealed marked
heterogeneity, impeding the completion of integrated molecular and clinical maps for each …

Treatment of muscle‐invasive and advanced bladder cancer in 2020

VG Patel, WK Oh, MD Galsky - CA: a cancer journal for …, 2020 - Wiley Online Library
Bladder cancer accounts for nearly 170,000 deaths worldwide annually. For over 4 decades,
the systemic management of muscle‐invasive and advanced bladder cancer has primarily …

The 2021 updated European Association of Urology guidelines on metastatic urothelial carcinoma

R Cathomas, A Lorch, HM Bruins, EM Compérat… - European urology, 2022 - Elsevier
Context Treatment of metastatic urothelial carcinoma is currently undergoing a rapid
evolution. Objective This overview presents the updated European Association of Urology …

[HTML][HTML] Applications of single-cell sequencing in cancer research: progress and perspectives

Y Lei, R Tang, J Xu, W Wang, B Zhang, J Liu… - Journal of hematology & …, 2021 - Springer
Single-cell sequencing, including genomics, transcriptomics, epigenomics, proteomics and
metabolomics sequencing, is a powerful tool to decipher the cellular and molecular …