Sleep disturbance is the most prominent symptom in depressive patients and was formerly
regarded as a main secondary manifestation of depression. However, many longitudinal …

Since ancient times it is known that melancholia and sleep disturbances co-occur. The
introduction of polysomnography into psychiatric research confirmed a disturbance of sleep …

Purpose Insomnia is problematic for older adults. After behavioral modifications fail to show
adequate response, pharmacologic options are used. The pharmacokinetics of agents used …

A systematic literature review and meta-analyses (where appropriate) were performed and
the GRADE approach was used to update the previous American Academy of Sleep …

Sleep abnormalities are associated with acute and chronic use of addictive substances.
Although sleep complaints associated with use and abstinence from addictive substances …

4 Die Diagnostik soll eine umfassende Anamnese inklusive einer Abklärung körperlicher
und psychischer Erkrankungen, eine körperliche Untersuchung sowie den Einsatz von …

Background Although originally marketed as safe alternatives to the habit-forming
benzodiazepines, growing numbers of zaleplon, zolpidem, and zopiclone (“Z-drugs”) clinical …

Abstract Problem/Condition: Drug overdose is the leading cause of injury death in the United
States. The death rate from drug overdose in the United States more than doubled during …

PROBLEM: Overdoses involving prescription drugs in the United States have reached
epidemic proportions over the past 20years. METHODS: This review categorizes and …

Background Use of sedatives may increase risk of death in opioid users. The aim of the
study was to assess whether prescription of sedatives may be associated with mortality in …