Depressive and other adverse CNS effects of fluoroquinolones

P Wierzbiński, J Hubska, M Henzler, B Kucharski… - Pharmaceuticals, 2023 - mdpi.com
Fluoroquinolones (FQs) are widely used drugs around the world. This is a result of their
broad spectrum of antibacterial activity, high bioavailability, and known efficacy. Since they …

Fluoroquinolones-Associated disability: it is not all in your head

MZ Freeman, DN Cannizzaro, LF Naughton, C Bove - NeuroSci, 2021 - mdpi.com
Fluoroquinolones (FQs) are a broad class of antibiotics typically prescribed for bacterial
infections, including infections for which their use is discouraged. The FDA has proposed the …

Enoxacin induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression

AL Rocha, TI de Lima, GP de Souza, RO Corrêa… - Science …, 2020 - science.org
MicroRNAs (miRNAs) have been implicated in oxidative metabolism and brown/beige
adipocyte identity. Here, we tested whether widespread changes in miRNA expression …

Adverse effects of fluoroquinolones: a retrospective cohort study in a South Indian tertiary healthcare facility

B Mathews, AA Thalody, SS Miraj, V Kunhikatta, M Rao… - Antibiotics, 2019 - mdpi.com
The Food and Drug Administration (FDA) safety review revealed that the use of
fluoroquinolones (FQs) is linked with disabling and potentially permanent serious adverse …

Association between initiation of fluoroquinolones and hospital admission or emergency department visit for suicidality: population based cohort study

J Wang, JJ Gagne, S Kattinakere-Sreedhara… - bmj, 2022 - bmj.com
Objective To evaluate the association between initiation of fluoroquinolones and hospital
admission or emergency department visit for suicidality. Design Population based cohort …

3, 3′, 5, 5′-Tetramethylbenzidine assisted construction of a label-free colorimetric and ratiometric fluorescent dual-channel sensor for the detection of levofloxacin

J Liao, Y Fan, S Deng, Z Yu, R Meng, L Jia - Microchemical Journal, 2023 - Elsevier
A colorimetric and ratiometric fluorescent dual-channel sensor was constructed for
levofloxacin (LVFX) detection only using 3, 3′, 5, 5′-tetramethylbenzidine (TMB). LVFX …

Psychiatric disorders associated with fluoroquinolones: a pharmacovigilance analysis of the FDA adverse event reporting system database

WL Xie, ML Ge, D Chen, GQ Chen, YX Mei… - Frontiers in …, 2024 - frontiersin.org
Background Fluoroquinolones are broad-spectrum antibiotics with significant antimicrobial
activity. Despite their therapeutic benefits, they are associated with a range of adverse drug …

Moxifloxacin-induced acute psychosis: A case report with literature review

F Mazhar, S Akram, N Haider - Journal of research in pharmacy …, 2016 - journals.lww.com
Third generation quinolones are extensively used to treat a variety of common bacterial
infections. Due to their extensive use in clinical practice, an increase in neuropsychiatric …

Association Between Oral Fluoroquinolones and Neuropsychiatric Events: Self‐Controlled Case Series With Active Comparator Design

Y Zhang, M Fan, NTY Tsie, EHM Lee… - … and drug safety, 2024 - Wiley Online Library
Purpose The evidence of the neuropsychiatric effects associated with fluoroquinolones is
mainly supported by case reports. Population‐based evidence remains largely limited. We …

Hypoglycemia and anxiolysis mediated by levofloxacin treatment in diabetic rats

P Singh, V Walia, PK Verma - Journal of Diabetes & Metabolic Disorders, 2023 - Springer
Purpose The present study was designed to determine the effect of levofloxacin (LVX)
treatment on the blood glucose level, insulin sensitivity, anxiety level, nitrite and MDA level …