Natural products derived from microorganisms serve as a vital resource of valuable
pharmaceuticals and therapeutic agents. Streptomyces is the most ubiquitous bacterial …

Natural products have historically been of crucial importance in the identification and
development of antibacterial agents. Interest in these systems has waned in recent years …

The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …

Drug discovery is based on bioactivity screening of natural sources, traditionally represented
by bacteria fungi and plants. Bioactive natural products and their secondary metabolites …

Recent genome sequencing efforts have led to the rapid accumulation of uncharacterized or
“orphaned” secondary metabolic biosynthesis gene clusters (BGCs) in public databases …

Despite the importance of microbial natural products for human health, only a few bacterial
genera have been mined for the new natural products needed to overcome the urgent threat …

Streptomyces are Gram-positive bacteria of significant industrial importance due to their
ability to produce a wide range of antibiotics and bioactive secondary metabolites. Recent …

The role and contributions of natural products chemistry in advancements of the physical
and biological sciences, its interdisciplinary domains, and emerging of new avenues by …

Drug discovery from marine natural products has experienced a revival since the beginning
of this century. To be successful in this field, rapid dereplication (identification of already …

For a long time, it was believed that a healthy plant did not harbor any microorganisms
within its tissues, as these were often considered detrimental for the plant. In the last three …