Alzheimer's disease (AD) is one of the biggest human health threats due to increases in
aging of the global population. Unfortunately, drugs for treating AD have been largely …

Diabetes mellitus is a disease that affects millions of people worldwide and its prevalence is
estimated to rise in the future. Billions of dollars are spent each year around the world in …

Background: Sodium glucose transporter type 2 inhibitors may reduce cardiovascular events
in type 2 diabetes. Our study aimed to determine the effect of the sodium glucose transporter …

Thiazolidinediones have been introduced in the treatment of type 2 diabetes mellitus
(T2DM) since the late 1990s. Although troglitazone was withdrawn from the market a few …

The number of bariatric surgical procedures performed has increased dramatically. This
review discusses the clinical and physiological changes, and in particular, the mechanisms …

Objective Dapagliflozin was the first drug in a class of therapies that took a new approach to
glycemic control in adults with type 2 diabetes (T2D). It is an inhibitor of the sodium glucose …

The kidneys play a major role in glucose homeostasis through its utilization,
gluconeogenesis, and reabsorption via sodium glucose cotransporters (SGLTs). The …

Introduction: The cytochrome P4502C enzymes account for the metabolism of approximately
20% of therapeutic drugs including certain oral antidiabetic drugs (OADs). Areas covered …

Biomedical research on the brain has led to many discoveries and developments, such as
understanding human consciousness and the mind and overcoming brain diseases …

The purpose of this study is to derive an optimal drug release formulation with human
clinical bioequivalence in developing a sitagliptin phosphate monohydrate-dapagliflozin …