Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

The medical management of paediatric Crohn's disease: an ECCO-ESPGHAN guideline update

PF Van Rheenen, M Aloi, A Assa… - Journal of Crohn's …, 2021 - academic.oup.com
Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn's disease [CD]. Methods We …

A randomized trial comparing the specific carbohydrate diet to a Mediterranean diet in adults with Crohn's disease

JD Lewis, RS Sandler, C Brotherton, C Brensinger, H Li… - Gastroenterology, 2021 - Elsevier
Background & Aims This study compared the effectiveness of the Specific Carbohydrate Diet
(SCD) to the Mediterranean diet (MD) as treatment for Crohn's disease (CD) with mild to …

Gut microbiota and IBD: causation or correlation?

J Ni, GD Wu, L Albenberg, VT Tomov - Nature reviews Gastroenterology …, 2017 - nature.com
A general consensus exists that IBD is associated with compositional and metabolic
changes in the intestinal microbiota (dysbiosis). However, a direct causal relationship …

ESPEN guideline: Clinical nutrition in inflammatory bowel disease

A Forbes, J Escher, X Hébuterne, S Kłęk, Z Krznaric… - Clinical Nutrition, 2017 - Elsevier
Introduction The ESPEN guideline presents a multidisciplinary focus on clinical nutrition in
inflammatory bowel disease (IBD). Methodology The guideline is based on extensive …

Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases

A Levine, RS Boneh, E Wine - Gut, 2018 - gut.bmj.com
Recent advances in basic and clinical science over the last 3 years have dramatically
altered our appreciation of the role of diet in inflammatory bowel diseases (IBD). The marked …

[HTML][HTML] Inflammation, antibiotics, and diet as environmental stressors of the gut microbiome in pediatric Crohn's disease

JD Lewis, EZ Chen, RN Baldassano, AR Otley… - Cell host & …, 2015 - cell.com
Abnormal composition of intestinal bacteria—" dysbiosis"—is characteristic of Crohn's
disease. Disease treatments include dietary changes and immunosuppressive anti-TNFα …

Inflammatory bowel disease in children and adolescents

MJ Rosen, A Dhawan, SA Saeed - JAMA pediatrics, 2015 - jamanetwork.com
The inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn disease, are
chronic inflammatory disorders of the gastrointestinal tract most often diagnosed in …

Escherichia coli Pathobionts Associated with Inflammatory Bowel Disease

HC Mirsepasi-Lauridsen, BA Vallance… - Clinical microbiology …, 2019 - Am Soc Microbiol
Gut bacteria play a key role in initiating and maintaining the inflammatory process in the gut
tissues of inflammatory bowel disease (IBD) patients, by supplying antigens or other …