Regenerative medicine aims to repair and regenerate damaged cells, tissues, and organs in
order to restore function. Regeneration can be obtained either by cell replacement or by …

A variety of paracrine signals create networks within the myocardium and mediate
intercellular communications. Indeed, paracrine stimulation of the endogenous regenerative …

Placenta-derived mesenchymal stromal cells (MSC) have attracted more attention for their
immune modulatory properties and poor immunogenicity, which makes them suitable for …

Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties
demonstrated in vitro and in vivo in various diseases in which the dysregulated immune …

Ischemia/reperfusion injury (IRI) represents one of the leading causes of primary non-
function acute liver transplantation failure. IRI, generated by an interruption of organ blood …

Objectives: To define the features of human amniotic mesenchymal stromal cell secretome
and its protective properties in experimental models of acute brain injury. Design …

Growing evidence suggests a mechanistic link between inflammation and the development
and progression of fibrotic processes. Mesenchymal stromal cells derived from the human …

Background Hyperpigmentation of skin is caused by an imbalance between the
melanosome/melanin synthesis in melanocytes and the melanosome/melanin degradation …

Mesenchymal stromal cells (MSC) from the amniotic membrane of human term placenta
(hAMSC), and the conditioned medium generated from their culture (CM-hAMSC) offer …

Background It is now well established that factors (free or in extracellular vesicles) secreted
by mesenchymal stromal cells (MSC) are important mediators of MSC regenerative actions …