Behavioural genetics methods
EA Willoughby, TJC Polderman… - Nature Reviews Methods …, 2023 - nature.com
The question of why people show individual differences in their behaviours and capacities
has intrigued researchers for centuries. Behaviour genetics offers us various methods to …
has intrigued researchers for centuries. Behaviour genetics offers us various methods to …
Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study
E Friligkou, S Løkhammer, B Cabrera-Mendoza… - Nature Genetics, 2024 - nature.com
We leveraged information from more than 1.2 million participants, including 97,383 cases, to
investigate the genetics of anxiety disorders across five continental groups. Through …
investigate the genetics of anxiety disorders across five continental groups. Through …
[HTML][HTML] Cerebral Palsy as a Childhood-onset Neurologic Disorder caused by both genetic and environmental factors.
Cerebral palsy (CP) is a clinical term used to describe a spectrum of movement and posture
disorders resulting from non-progressive disturbances in the developing fetal brain. The …
disorders resulting from non-progressive disturbances in the developing fetal brain. The …
Effects of sex and gender on the etiologies and presentation of select internalizing psychopathologies
The internalizing spectrum encompasses a subset of psychopathologies characterized by
emotional liability, anhedonia, anxiousness, distress, and fear, and includes, among others …
emotional liability, anhedonia, anxiousness, distress, and fear, and includes, among others …
Building machine learning prediction models for well-being using predictors from the exposome and genome in a population cohort
Effective personalized well-being interventions require the ability to predict who will thrive or
not, and the understanding of underlying mechanisms. Here, using longitudinal data of a …
not, and the understanding of underlying mechanisms. Here, using longitudinal data of a …
An honest reckoning with the amygdala and mental illness
AS Fox, AJ Shackman - American Journal of Psychiatry, 2024 - psychiatryonline.org
Anxiety disorders are a leading source of human misery, morbidity, and premature mortality.
Existing treatments are far from curative for many, underscoring the need to clarify the …
Existing treatments are far from curative for many, underscoring the need to clarify the …
Genetic Architectures of Adolescent Depression Trajectories in 2 Longitudinal Population Cohorts
Importance Adolescent depression is characterized by diverse symptom trajectories over
time and has a strong genetic influence. Research has determined genetic overlap between …
time and has a strong genetic influence. Research has determined genetic overlap between …
A Mechanistic Investigation of the N-Hydroxyphthalimide Catalyzed Benzylic Oxidation Mediated by Sodium Chlorite
T Grunshaw, SH Wood, S Sproules… - The Journal of …, 2024 - ACS Publications
A detailed investigation into the mechanistic course of N-hydroxyphthalimide catalyzed
oxidation of benzylic centers using sodium chlorite as the stoichiometric oxidant is reported …
oxidation of benzylic centers using sodium chlorite as the stoichiometric oxidant is reported …
Breakfast skipping is linked to a higher risk of major depressive disorder and the role of gut microbes: a mendelian randomization study
Background Observational studies have indicated that breakfast skipping and gut
microbiome dysbiosis are associated with a higher risk of major depressive disorder (MDD) …
microbiome dysbiosis are associated with a higher risk of major depressive disorder (MDD) …
Immuno-metabolic depression: from concept to implementation
Major depressive disorder is a common, disabling mental disorder characterized by
extensive etiological and phenotypic heterogeneity. This heterogeneity makes treatment …
extensive etiological and phenotypic heterogeneity. This heterogeneity makes treatment …