Calcium Pyrophosphate Crystal Formation and Deposition: Where Do we Stand and What Does the Future hold?

S Sirotti, A Scanu, T Pascart, T Niessink… - Current Rheumatology …, 2024 - Springer
Purpose of the review Although calcium pyrophosphate deposition (CPPD) has been known
since the 1960s, our understanding of its pathogenesis remains rudimentary. This review …

Raman Spectroscopy Reveals Microparticles in Synovial Fluids of Patients With Suspected Implant‐Related Complications

T Niessink, JWA Schoenmakers… - Journal of Raman …, 2024 - Wiley Online Library
Prosthetic implant‐associated inflammation and failure can be caused by bacterial infections
and mechanical wear of the prosthesis. Currently, there is no diagnostic modality that allows …

An objective diagnosis of gout and calcium pyrophosphate deposition disease with machine learning of Raman spectra acquired in a point-of-care setting

T Niessink, TL Jansen, FAW Coumans… - …, 2024 - academic.oup.com
Objective Raman spectroscopy is proposed as a next-generation method for the
identification of monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in …

Synovial fluid analysis with compensated polarization light microscopy: a physics approach to quantitative understanding of birefringence, polarization, and Maltese …

T Niessink, TL Jansen, M Kleinherenbrink… - Clinical …, 2024 - Springer
Polarized light microscopic identification of monosodium urate (MSU) or calcium
pyrophosphate (CPP) crystals in synovial fluid is considered sufficient proof for diagnosing a …

[PDF][PDF] Parts of this chapter are published as: Synovial fluid analysis with compensated polarization light microscopy: A physics approach to quantitative understanding …

T Niessink, TL Jansen, M Janssen… - A new perspective on … - research.utwente.nl
Crystalline arthropathies are crystal-associated auto-inflammatory rheumatic diseases. Gout
and calcium pyrophosphate deposition disease (CPPD) are the most common forms of …

[PDF][PDF] Automated identification of pathologic crystals

T Niessink, TL Jansen, FAW Coumans… - A new perspective on … - research.utwente.nl
Raman spectroscopy is proposed as a next-generation method for the identification of
monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals in synovial fluid. As …