SUMMARY 1 Intrauterine growth restriction (IUGR) has been associated with poor perinatal
health outcomes. Animal models have been used to investigate why IUGR is associated with …

Epidemiology formed the basis of 'the Barker hypothesis', the concept of 'developmental
programming'and today's discipline of the Developmental Origins of Health and Disease …

Pregnant ewes were fed either a 50% nutrient‐restricted (NR; n= 8) or a control 100%(C; n=
8) diet from day 28 to day 78 of gestation (dGA; term= 150 dGA). Lambs were born naturally …

Fetal growth restriction (FGR) is a major cause of stillbirth, prematurity and impaired
neurodevelopment. Its etiology is multifactorial, but many cases are related to impaired …

The developmental origins of health and disease theory is based on evidence that a
suboptimal environment during fetal and neonatal development can significantly impact the …

Over recent years, studies have demonstrated links between risk of cardiovascular disease
in adulthood and adverse events that occurred very early in life during fetal development …

Epidemiological studies have clearly demonstrated a strong association between low birth
weight and long‐term renal disease. A potential mediator of this long‐term risk is a reduction …

The etiology of hypertension historically includes 2 components: genetics and lifestyle.
However, recent epidemiologic studies report an inverse relationship between birth weight …

Impaired kidney growth in low-birth-weight children: Distinct effects of maturity and weight for
gestational age. Background Low birth weight is an important risk factor for hypertension …

Low birth weight has been shown to be associated with later renal function, but it is unclear
to what extent this is explained by other established kidney disease risk factors. Here we …