Circadian rhythms, sleep deprivation, and human performance

N Goel, M Basner, H Rao, DF Dinges - Progress in molecular biology and …, 2013 - Elsevier
Much of the current science on, and mathematical modeling of, dynamic changes in human
performance within and between days is dominated by the two-process model of sleep …

Epidemiology of the human circadian clock

T Roenneberg, T Kuehnle, M Juda, T Kantermann… - Sleep medicine …, 2007 - Elsevier
Humans show large inter-individual differences in organising their behaviour within the 24-h
day—this is most obvious in their preferred timing of sleep and wakefulness. Sleep and …

Mutation of the human circadian clock gene CRY1 in familial delayed sleep phase disorder

A Patke, PJ Murphy, OE Onat, AC Krieger, T Özçelik… - Cell, 2017 - cell.com
Patterns of daily human activity are controlled by an intrinsic circadian clock that promotes∼
24 hr rhythms in many behavioral and physiological processes. This system is altered in …

Sleep: a health imperative

FS Luyster, PJ Strollo Jr, PC Zee, JK Walsh - Sleep, 2012 - academic.oup.com
Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing
and underappreciated determinant of health status. Sleep deprivation contributes to a …

Life between clocks: daily temporal patterns of human chronotypes

T Roenneberg, A Wirz-Justice… - Journal of biological …, 2003 - journals.sagepub.com
Human behavior shows large interindividual variation in temporal organization. Extreme
“larks” wake up when extreme “owls” fall asleep. These chronotypes are attributed to …

Electroencephalogram and electrocardiograph assessment of mental fatigue in a driving simulator

C Zhao, M Zhao, J Liu, C Zheng - Accident Analysis & Prevention, 2012 - Elsevier
Mental fatigue is a contributing factor to some serious transportation crashes. In this study,
we measured mental fatigue in drivers using electroencephalogram (EEG) and …

Genetic basis of chronotype in humans: insights from three landmark GWAS

DA Kalmbach, LD Schneider, J Cheung, SJ Bertrand… - Sleep, 2017 - academic.oup.com
Abstract Study Objectives: Chronotype, or diurnal preference, refers to behavioral
manifestations of the endogenous circadian system that governs preferred timing of sleep …

Evening chronotype is associated with changes in eating behavior, more sleep apnea, and increased stress hormones in short sleeping obese individuals

EA Lucassen, X Zhao, KI Rother, MS Mattingly… - PloS one, 2013 - journals.plos.org
Background Short sleep duration and decreased sleep quality are emerging risk factors for
obesity and its associated morbidities. Chronotype, an attribute that reflects individual …

Beyond sleep: A multidimensional model of chronotype

S Chauhan, R Norbury, KC Faßbender… - Neuroscience & …, 2023 - Elsevier
Chronotype can be defined as an expression or proxy for circadian rhythms of varied
mechanisms, for example in body temperature, cortisol secretion, cognitive functions, eating …

Entrainment of the human circadian clock

T Roenneberg, M Merrow - Cold Spring Harbor symposia on …, 2007 - symposium.cshlp.org
Humans are an excellent model system for studying entrainment of the circadian clock in the
real world. Unlike the situation in laboratory experiments, entrainment under natural …