Circadian rhythms, sleep deprivation, and human performance
Much of the current science on, and mathematical modeling of, dynamic changes in human
performance within and between days is dominated by the two-process model of sleep …
performance within and between days is dominated by the two-process model of sleep …
Epidemiology of the human circadian clock
Humans show large inter-individual differences in organising their behaviour within the 24-h
day—this is most obvious in their preferred timing of sleep and wakefulness. Sleep and …
day—this is most obvious in their preferred timing of sleep and wakefulness. Sleep and …
Mutation of the human circadian clock gene CRY1 in familial delayed sleep phase disorder
A Patke, PJ Murphy, OE Onat, AC Krieger, T Özçelik… - Cell, 2017 - cell.com
Patterns of daily human activity are controlled by an intrinsic circadian clock that promotes∼
24 hr rhythms in many behavioral and physiological processes. This system is altered in …
24 hr rhythms in many behavioral and physiological processes. This system is altered in …
Sleep: a health imperative
Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing
and underappreciated determinant of health status. Sleep deprivation contributes to a …
and underappreciated determinant of health status. Sleep deprivation contributes to a …
Life between clocks: daily temporal patterns of human chronotypes
T Roenneberg, A Wirz-Justice… - Journal of biological …, 2003 - journals.sagepub.com
Human behavior shows large interindividual variation in temporal organization. Extreme
“larks” wake up when extreme “owls” fall asleep. These chronotypes are attributed to …
“larks” wake up when extreme “owls” fall asleep. These chronotypes are attributed to …
Electroencephalogram and electrocardiograph assessment of mental fatigue in a driving simulator
C Zhao, M Zhao, J Liu, C Zheng - Accident Analysis & Prevention, 2012 - Elsevier
Mental fatigue is a contributing factor to some serious transportation crashes. In this study,
we measured mental fatigue in drivers using electroencephalogram (EEG) and …
we measured mental fatigue in drivers using electroencephalogram (EEG) and …
Genetic basis of chronotype in humans: insights from three landmark GWAS
DA Kalmbach, LD Schneider, J Cheung, SJ Bertrand… - Sleep, 2017 - academic.oup.com
Abstract Study Objectives: Chronotype, or diurnal preference, refers to behavioral
manifestations of the endogenous circadian system that governs preferred timing of sleep …
manifestations of the endogenous circadian system that governs preferred timing of sleep …
Evening chronotype is associated with changes in eating behavior, more sleep apnea, and increased stress hormones in short sleeping obese individuals
EA Lucassen, X Zhao, KI Rother, MS Mattingly… - PloS one, 2013 - journals.plos.org
Background Short sleep duration and decreased sleep quality are emerging risk factors for
obesity and its associated morbidities. Chronotype, an attribute that reflects individual …
obesity and its associated morbidities. Chronotype, an attribute that reflects individual …
Beyond sleep: A multidimensional model of chronotype
Chronotype can be defined as an expression or proxy for circadian rhythms of varied
mechanisms, for example in body temperature, cortisol secretion, cognitive functions, eating …
mechanisms, for example in body temperature, cortisol secretion, cognitive functions, eating …
Entrainment of the human circadian clock
T Roenneberg, M Merrow - Cold Spring Harbor symposia on …, 2007 - symposium.cshlp.org
Humans are an excellent model system for studying entrainment of the circadian clock in the
real world. Unlike the situation in laboratory experiments, entrainment under natural …
real world. Unlike the situation in laboratory experiments, entrainment under natural …