Body focused repetitive behavior disorders: behavioral models and neurobiological mechanisms
HG Okumuş, D Akdemir - Turkish Journal of Psychiatry, 2022 - pmc.ncbi.nlm.nih.gov
Objective: Body Focused Repetitive Behaviors (BFRB) is an umbrella term for undesirable,
repetitive motor activities such as Trichotillomania (TTM), Skin Picking Disorder (SPD), nail …
repetitive motor activities such as Trichotillomania (TTM), Skin Picking Disorder (SPD), nail …
Unraveling the mechanisms of deep-brain stimulation of the internal capsule in a mouse model
BJG van den Boom, A Elhazaz-Fernandez… - Nature …, 2023 - nature.com
Deep-brain stimulation (DBS) is an effective treatment for patients suffering from otherwise
therapy-resistant psychiatric disorders, including obsessive-compulsive disorder …
therapy-resistant psychiatric disorders, including obsessive-compulsive disorder …
Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making
Serotonin is critical for adapting behavior flexibly to meet changing environmental demands.
Cognitive flexibility is important for successful attainment of goals, as well as for social …
Cognitive flexibility is important for successful attainment of goals, as well as for social …
Association of environmental uncertainty with altered decision-making and learning mechanisms in youths with obsessive-compulsive disorder
AA Marzuki, I Tomić, SHY Ip, J Gottwald… - JAMA network …, 2021 - jamanetwork.com
Importance Adults with obsessive-compulsive disorder (OCD) display perseverative
behavior in stable environments but exhibit vacillating choice when payoffs are uncertain …
behavior in stable environments but exhibit vacillating choice when payoffs are uncertain …
Distinct patterns of abnormal lateral orbitofrontal cortex activity during compulsive grooming and reversal learning normalize after fluoxetine
Background Patients with obsessive-compulsive disorder (OCD) display disrupted
performance and abnormal lateral orbitofrontal cortex (LOFC) activity during reversal …
performance and abnormal lateral orbitofrontal cortex (LOFC) activity during reversal …
Neural circuits in goal-directed and habitual behavior: Implications for circuit dysfunction in obsessive-compulsive disorder
LD Simmler, T Ozawa - Neurochemistry international, 2019 - Elsevier
Goal-directed and habitual actions are essential for normal functioning in everyday life. Goal-
directed behaviors are actions that are executed to achieve specific goals. With repetition …
directed behaviors are actions that are executed to achieve specific goals. With repetition …
Disruption of prepulse inhibition is associated with compulsive behavior severity and nucleus accumbens dopamine receptor changes in Sapap3 knockout mice
EE Manning, AY Wang, LM Saikali, AS Winner… - Scientific Reports, 2021 - nature.com
Obsessive compulsive disorder (OCD) is associated with disruption of sensorimotor gating,
which may contribute to difficulties inhibiting intrusive thoughts and compulsive rituals …
which may contribute to difficulties inhibiting intrusive thoughts and compulsive rituals …
The Sapap3−/− mouse reconsidered as a comorbid model expressing a spectrum of pathological repetitive behaviours
H Lamothe, C Schreiweis… - Translational …, 2023 - nature.com
Symptom comorbidity is present amongst neuropsychiatric disorders with repetitive
behaviours, complicating clinical diagnosis and impeding appropriate treatments. This is of …
behaviours, complicating clinical diagnosis and impeding appropriate treatments. This is of …
Psychiatric symptoms influence reward‐seeking and loss‐avoidance decision‐making through common and distinct computational processes
S Suzuki, Y Yamashita… - Psychiatry and Clinical …, 2021 - Wiley Online Library
Aim Psychiatric symptoms are often accompanied by impairments in decision‐making to
attain rewards and avoid losses. However, due to the complex nature of mental disorders …
attain rewards and avoid losses. However, due to the complex nature of mental disorders …