Rheumatoid arthritis—common origins, divergent mechanisms

EM Gravallese, GS Firestein - New England Journal of Medicine, 2023 - Mass Medical Soc
Rheumatoid Arthritis — Common Origins, Divergent Mechanisms | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

L Ferrucci, E Fabbri - Nature Reviews Cardiology, 2018 - nature.com
Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Pathogenetic insights from the treatment of rheumatoid arthritis

IB McInnes, G Schett - The Lancet, 2017 - thelancet.com
Rheumatoid arthritis is a chronic autoimmune disease that causes progressive articular
damage, functional loss, and comorbidity. The development of effective biologics and small …

EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 …

R Agca, SC Heslinga, S Rollefstad… - Annals of the …, 2017 - ard.bmj.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint disorders (IJD) have
increased cardiovascular disease (CVD) risk compared with the general population. In …

The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis …

C Roubille, V Richer, T Starnino, C McCourt… - Annals of the …, 2015 - ard.bmj.com
The objective of this systematic literature review was to determine the association between
cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and …

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization–systematic review and recommendations from the HS ALLIANCE working …

CC Zouboulis, FG Bechara… - Journal of the …, 2019 - Wiley Online Library
Hidradenitis suppurativa (HS)/acne inversa is a debilitating chronic disease that remains
poorly understood and difficult to manage. Clinical practice is variable, and there is a need …

Targeting IL-17 and TH17 cells in chronic inflammation

P Miossec, JK Kolls - Nature reviews Drug discovery, 2012 - nature.com
The key role of interleukin-17 (IL-17) and T helper 17 (TH17) cells in tissue inflammation,
autoimmunity and host defence led to the experimental targeting of these molecules in …

The Potential for Repurposing Anti-TNF as a Therapy for the Treatment of COVID-19

PC Robinson, DFL Liew, JW Liew, C Monaco… - Med, 2020 - cell.com
Summary Coronavirus disease 2019 (COVID-19) currently has few effective treatments.
Given the uncertainty surrounding the effectiveness and uptake of a vaccine, it is important …

Cardiovascular comorbidity in rheumatic diseases

MT Nurmohamed, M Heslinga, GD Kitas - Nature Reviews …, 2015 - nature.com
Patients with rheumatoid arthritis (RA) and other inflammatory joint diseases (IJDs) have an
increased risk of premature death compared with the general population, mainly because of …