Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

Coenzyme Q (CoQ, or ubiquinone) is a remarkable lipid that plays an essential role in
mitochondria as an electron shuttle between complexes I and II of the respiratory chain, and …

Identification of single-gene causes of steroid-resistant nephrotic syndrome (SRNS) has
furthered the understanding of the pathogenesis of this disease. Here, using a combination …

Steroid-resistant nephrotic syndrome (SRNS) is a frequent cause of end-stage renal failure.
Identification of single-gene causes of SRNS has generated some insights into its …

Vitamin K occurs in the natural world in several forms, including a plant form, phylloquinone
(PK), and a bacterial form, menaquinones (MKs). In many species, including humans, PK is …

Coenzyme Q 10 is a remarkable lipid involved in many cellular processes such as energy
production through the mitochondrial respiratory chain (RC), beta-oxidation of fatty acids …

Background Multiple-system atrophy is an intractable neurodegenerative disease
characterized by autonomic failure in addition to various combinations of parkinsonism …

Coenzyme Q (CoQ) is a unique electron carrier in the mitochondrial respiratory chain, which
is synthesized on-site by a nuclear encoded multiprotein complex. CoQ receives electrons …

Mitochondria are cytoplasmic organelles, which generate energy as heat and ATP, the
universal energy currency of the cell. This process is carried out by coupling electron …

Abstract Primary coenzyme Q 10 (CoQ 10) deficiency includes a group of rare autosomal
recessive disorders primarily characterized by neurological and muscular symptoms. Rarely …