Pancreatic cancer: Advances and challenges

CJ Halbrook, CA Lyssiotis, MP di Magliano, A Maitra - Cell, 2023 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers. Significant
efforts have largely defined major genetic factors driving PDAC pathogenesis and …

Pancreatic cancer

JD Mizrahi, R Surana, JW Valle, RT Shroff - The Lancet, 2020 - thelancet.com
Pancreatic cancer is a highly fatal disease with a 5-year survival rate of approximately 10%
in the USA, and it is becoming an increasingly common cause of cancer mortality. Risk …

[HTML][HTML] A deep learning algorithm to predict risk of pancreatic cancer from disease trajectories

D Placido, B Yuan, JX Hjaltelin, C Zheng, AD Haue… - Nature medicine, 2023 - nature.com
Pancreatic cancer is an aggressive disease that typically presents late with poor outcomes,
indicating a pronounced need for early detection. In this study, we applied artificial …

Large-scale pancreatic cancer detection via non-contrast CT and deep learning

K Cao, Y Xia, J Yao, X Han, L Lambert, T Zhang… - Nature medicine, 2023 - nature.com
Pancreatic ductal adenocarcinoma (PDAC), the most deadly solid malignancy, is typically
detected late and at an inoperable stage. Early or incidental detection is associated with …

[HTML][HTML] Proteogenomic characterization of pancreatic ductal adenocarcinoma

L Cao, C Huang, DC Zhou, Y Hu, TM Lih, SR Savage… - Cell, 2021 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with poor patient
survival. Toward understanding the underlying molecular alterations that drive PDAC …

Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China

W Liang, W Guan, R Chen, W Wang, J Li, K Xu… - The lancet …, 2020 - thelancet.com
China and the rest of the world are experiencing an outbreak of a novel betacoronavirus
known as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). 1 By Feb 12 …

Advances in the epidemiology of pancreatic cancer: Trends, risk factors, screening, and prognosis

J Cai, H Chen, M Lu, Y Zhang, B Lu, L You, T Zhang… - Cancer letters, 2021 - Elsevier
Pancreatic cancer is a malignancy with poor prognosis and high mortality. The recent
increase in pancreatic cancer incidence and mortality has resulted in an increased number …

Medical image augmentation for lesion detection using a texture-constrained multichannel progressive GAN

Q Guan, Y Chen, Z Wei, AA Heidari, H Hu… - Computers in Biology …, 2022 - Elsevier
Lesion detectors based on deep learning can assist doctors in diagnosing diseases.
However, the performance of current detectors is likely to be unsatisfactory due to the …

[HTML][HTML] Artificial intelligence in pancreatic cancer

B Huang, H Huang, S Zhang, D Zhang, Q Shi, J Liu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic cancer is the deadliest disease, with a five-year overall survival rate of just 11%.
The pancreatic cancer patients diagnosed with early screening have a median overall …

Pancreatic cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

T Conroy, P Pfeiffer, V Vilgrain, A Lamarca… - Annals of …, 2023 - annalsofoncology.org
The opportunity to detect pancreatic cancer (PC) when potentially curable depends on early
diagnosis and an ability to identify and screen high-risk populations before symptoms arise …