[HTML][HTML] Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets

C Gao, J Jiang, Y Tan, S Chen - Signal transduction and targeted …, 2023 - nature.com
Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …

Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue

TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …

Physiology of astroglia

A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …

Microglial control of astrocytes in response to microbial metabolites

V Rothhammer, DM Borucki, EC Tjon, MC Takenaka… - Nature, 2018 - nature.com
Microglia and astrocytes modulate inflammation and neurodegeneration in the central
nervous system (CNS),–. Microglia modulate pro-inflammatory and neurotoxic activities in …

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Neuroinflammation in the central nervous system: Symphony of glial cells

Q Yang, J Zhou - Glia, 2019 - Wiley Online Library
Neuroinflammation in the central nervous system (CNS) is an important subject of
neuroimmunological research. Emerging evidence suggests that neuroinflammation is a key …

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

V Rothhammer, ID Mascanfroni, L Bunse… - Nature medicine, 2016 - nature.com
Astrocytes have important roles in the central nervous system (CNS) during health and
disease. Through genome-wide analyses we detected a transcriptional response to type I …

[HTML][HTML] The roles of Eph receptors, neuropilin-1, P2X7, and CD147 in COVID-19-associated neurodegenerative diseases: inflammasome and JaK inhibitors as …

H Zalpoor, A Akbari, A Samei… - Cellular & Molecular …, 2022 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic has spread worldwide, and
finding a safe therapeutic strategy and effective vaccine is critical to overcoming severe …

Toll-like receptors in the pathogenesis of neuroinflammation

V Kumar - Journal of Neuroimmunology, 2019 - Elsevier
Toll-like receptors (TLRs) are discovered as crucial pattern recognition receptors (PRRs)
involved in the recognition of pathogen-associated molecular patterns (PAMPs). Later …

Oxidative stress‐related mechanisms in schizophrenia pathogenesis and new treatment perspectives

EA Ermakov, EM Dmitrieva… - Oxidative Medicine …, 2021 - Wiley Online Library
Schizophrenia is recognized to be a highly heterogeneous disease at various levels, from
genetics to clinical manifestations and treatment sensitivity. This heterogeneity is also …