Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

Menopause is one of the most significant events in a woman's life and brings in a number of
physiological changes that affect the life of a woman permanently. There have been a lot of …

Estrogen is a fundamental regulator of the metabolic system of the female brain and body.
Within the brain, estrogen regulates glucose transport, aerobic glycolysis, and mitochondrial …

A New York Times Notable Book: A psychologist's “gripping and thought-provoking” look at
how and why our brains sometimes fail us (Steven Pinker, author of How the Mind Works). In …

ContextSome observational data suggest that hormone replacement therapy (HRT) may
reduce the risk of cognitive decline and dementia but results have been conflicting …

Estrogen (E 2) has many effects in the central nervous system, including effects on anxiety
and depression behavior. This review will address effects of E 2 on behaviors related to …

Research in basic neuroscience has provided biological plausibility for the hypothesis that
estrogen replacement therapy (ERT) would protect against cognitive aging in healthy …

The origins and rationale of the Cambridge Neuropsychological Test Automated Battery
(CANTAB) as a cross-species translational instrument suitable for use in human …

Rationale: Soya foods are rich in isoflavone phytoestrogens with weak agonist activity at
oestrogen receptors. Oestrogen treatment has been found to improve memory in men …

Although there is now a substantial literature on the putative neuroprotective effects of
estrogen on cognitive functioning in postmenopausal women, it is replete with …