Taurine (a sulfur-containing β-amino acid), creatine (a metabolite of arginine, glycine and
methionine), carnosine (a dipeptide; β-alanyl-l-histidine), and 4-hydroxyproline (an imino …

Abstract Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-
protein nitrogen-containing compound of meat. The dipeptide is not only found in skeletal …

Context: Currently, the outcomes of the use of cisplatin in cancer therapy is limited by
nephrotoxicity. Objective: This study aims to investigate the nephroprotective role of …

Despite significant progress in the pathogenesis, diagnosis, treatment, and prevention of
cancer and neurodegenerative diseases, their occurrence and mortality are still high around …

Nephrotoxicity is one of the serious dose limiting side effects of cisplatin when used in the
treatment of various malignant conditions. Accumulating evidence suggests that oxidative …

The application of carnosine in medicine has been discussed since several years, but many
claims of therapeutic effects have not been substantiated by rigorous experimental …

Cisplatin, as an effective chemotherapeutic agent, is widely used to treat verious types of
cancers. Nephrotoxicity induced by cisplatin seriously limits its clinical application. Icariin, a …

The aim of current study was to assess the antioxidant and renoprotective effects of Stachys
pilifera Benth (SPB) hydroalcoholic extract on nephrotoxicity induced with cisplatin (CP) …

Fanconi's Syndrome (FS) is a disorder characterized by impaired renal proximal tubule
function. FS is associated with a vast defect in the renal reabsorption of several chemicals …

The aim of the present study was to evaluate the possible protective effect of polydatin (PD)
on cisplatin (Cis) induced oxidative stress in rats. Totally, thirty male Wistar albino rats were …