The rapid development of nanotechnology offers a variety of potential therapeutic strategies
for cancer treatment. High atomic element nanomaterials are often utilized as …

Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past
decade, there has been growing interest in using high Z (atomic number) elements …

Over the past decades, immunotherapy has demonstrated a prominent clinical efficacy in a
wide variety of human tumors. For many years, apoptosis has been considered a non …

Mitochondrial toxicity is an important safety endpoint in drug discovery. Models based solely
on chemical structure for predicting mitochondrial toxicity are currently limited in accuracy …

The endoplasmic reticulum (ER) is one of the most important cellular organelles and is
essential for cell homeostasis. Upon external stimulation, ER stress induces the unfolded …

Cancer is one of the greatest causes of death worldwide. With the development of surgery,
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …

Pathways governing protein homeostasis are involved in maintaining the structural,
quantitative, and functional stability of intracellular proteins and involve the ubiquitin …

Meat quality holds significant importance for both consumers and meat producers. Various
factors influence meat quality, and among them, mitochondria play a crucial role. Recent …

Autophagy, a double-edged sword for cell survival, is the research object on 2016 Nobel
Prize in Physiology or Medicine. Autophagy is a molecular mechanism for maintaining …

PERK is one of the transmembrane sensors of unfolded protein response (UPR) triggered
by ER stress. In this study, we evaluated the role of PERK in the sensitivity of hepatocellular …