Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
Pseudomonas aeruginosa evolutionary adaptation and diversification in cystic fibrosis chronic lung infections
Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …
[HTML][HTML] Adaptive evolution within gut microbiomes of healthy people
Natural selection shapes bacterial evolution in all environments. However, the extent to
which commensal bacteria diversify and adapt within the human gut remains unclear. Here …
which commensal bacteria diversify and adapt within the human gut remains unclear. Here …
The increasing threat of Pseudomonas aeruginosa high-risk clones
The increasing prevalence of chronic and hospital-acquired infections produced by
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …
multidrug-resistant (MDR) or extensively drug-resistant (XDR) Pseudomonas aeruginosa …
Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis
MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …
β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects
KA Glen, IL Lamont - Pathogens, 2021 - mdpi.com
Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …
and chronic infections. β-lactam antibiotics including penicillins, carbapenems …
The distribution of bacterial doubling times in the wild
Generation time varies widely across organisms and is an important factor in the life cycle,
life history and evolution of organisms. Although the doubling time (DT) has been estimated …
life history and evolution of organisms. Although the doubling time (DT) has been estimated …
Within-host evolution of bacterial pathogens
Whole-genome sequencing has opened the way for investigating the dynamics and
genomic evolution of bacterial pathogens during the colonization and infection of humans …
genomic evolution of bacterial pathogens during the colonization and infection of humans …
Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis
Little is known about how within-host evolution compares between genotypically different
strains of the same pathogenic species. We sequenced the whole genomes of 474 …
strains of the same pathogenic species. We sequenced the whole genomes of 474 …
Population genomics of bacterial host adaptation
Some bacteria can transfer to new host species, and this poses a risk to human health.
Indeed, an estimated 60% of all human pathogens have originated from other animal …
Indeed, an estimated 60% of all human pathogens have originated from other animal …