Plant polyphenols mechanisms of action on insulin resistance and against the loss of pancreatic beta cells

C Papuc, GV Goran, CN Predescu… - Critical reviews in …, 2021 - Taylor & Francis
Diabetes mellitus describes a group of metabolic disorders characterized by a prolonged
period hyperglycemia with long-lasting detrimental effects on the cardiovascular and …

[HTML][HTML] Natural polyphenols as targeted modulators in colon cancer: molecular mechanisms and applications

J Long, P Guan, X Hu, L Yang, L He, Q Lin… - Frontiers in …, 2021 - frontiersin.org
Colon cancer commonly develops from long-term chronic inflammation in the intestine and
seriously threatens human health. Natural polyphenols have been valued as a crucial …

[HTML][HTML] Glycolytic shift during West Nile virus infection provides new therapeutic opportunities

P Mingo-Casas, AB Blázquez… - Journal of …, 2023 - Springer
Background Viral rewiring of host bioenergetics and immunometabolism may provide novel
targets for therapeutic interventions against viral infections. Here, we have explored the …

[HTML][HTML] Cancer glycolytic dependence as a new target of olive leaf extract

J Ruzzolini, S Peppicelli, F Bianchini, E Andreucci… - Cancers, 2020 - mdpi.com
Oleuropein (Ole), the main bioactive phenolic component of Olea europaea L. has recently
attracted the scientific attention for its several beneficial properties, including its anticancer …

[HTML][HTML] Precision nutrition and cancer relapse prevention: a systematic literature review

C Reglero, G Reglero - Nutrients, 2019 - mdpi.com
Cancer mortality rates are undergoing a global downward trend; however, metastasis and
relapse after surgery and adjuvant treatments still correlate with poor prognosis and …

[HTML][HTML] Phlorotannins: novel orally administrated bioactive compounds that induce mitochondrial dysfunction and oxidative stress in cancer

L Simón, M Arazo-Rusindo, AFG Quest… - Antioxidants, 2023 - mdpi.com
Mitochondrial dysfunction is an interesting therapeutic target to help reduce cancer deaths,
and the use of bioactive compounds has emerged as a novel and safe approach to solve …

Single dose of a polyanhydride particle-based vaccine generates potent antigen-specific antitumor immune responses

EI Wafa, SM Geary, KA Ross, JT Goodman… - … of Pharmacology and …, 2019 - ASPET
Many factors affect vaccine efficacy. One of the most salient is the frequency and intervals of
vaccine administration. In this study, we assessed the vaccine administration modality for a …

[HTML][HTML] Biologically active metabolite(s) from haemolymph of red-headed centipede Scolopendra subspinipes possess broad spectrum antibacterial activity

SM Ali, NA Khan, K Sagathevan, A Anwar, R Siddiqui - AMB Express, 2019 - Springer
The discovery of novel antimicrobials from animal species under pollution is an area
untapped. Chinese red-headed centipede is one of the hardiest arthropod species …

[HTML][HTML] Biological activities of miracle berry supercritical extracts as metabolic regulators in chronic diseases

S Wagner, M Gómez de Cedrón… - International Journal of …, 2023 - mdpi.com
Synsepalum dulcificum (Richardella dulcifica) is a berry fruit from West Africa with the ability
to convert the sour taste into a sweet taste, and for this reason, the fruit is also known as the …

Mitochondria as target for tumor management of hemangioendothelioma

GM Gordillo, A Biswas, K Singh, A Sen… - Antioxidants & Redox …, 2021 - liebertpub.com
Aims: Hemangioendothelioma (HE) may be benign or malignant. Mouse
hemangioendothelioma endothelial (EOMA) cells are validated to study mechanisms in HE …