The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

[HTML][HTML] Studies on anticancer activities of antimicrobial peptides

DW Hoskin, A Ramamoorthy - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
In spite of great advances in cancer therapy, there is considerable current interest in
developing anticancer agents with a new mode of action because of the development of …

[HTML][HTML] Membrane-active host defense peptides–challenges and perspectives for the development of novel anticancer drugs

S Riedl, D Zweytick, K Lohner - Chemistry and physics of lipids, 2011 - Elsevier
Although much progress has been achieved in the development of cancer therapies in
recent decades, problems continue to arise particularly with respect to chemotherapy due to …

Antimicrobial peptides: versatile biological properties

M Pushpanathan, P Gunasekaran… - International journal of …, 2013 - Wiley Online Library
Antimicrobial peptides are diverse group of biologically active molecules with
multidimensional properties. In recent past, a wide variety of AMPs with diverse structures …

Saxitoxin, a toxic marine natural product that targets a multitude of receptors

LE Llewellyn - Natural product reports, 2006 - pubs.rsc.org
Covering: up to the end of 2005Saxitoxin (STX) was discovered early last century and can
contaminate seafood and drinking water, and over time has become an invaluable research …

[HTML][HTML] Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides

KCL Mulder, LA Lima, VJ Miranda, SC Dias… - Frontiers in …, 2013 - frontiersin.org
Cationic antimicrobial peptides (AMPs) and host defense peptides (HDPs) show vast
potential as peptide-based drugs. Great effort has been made in order to exploit their …

Antimicrobial peptides with anticancer activity: Today status, trends and their computational design

M Kordi, Z Borzouyi, S Chitsaz, M hadi Asmaei… - Archives of biochemistry …, 2023 - Elsevier
Some antimicrobial peptides have been shown to be able to inhibit the proliferation of
cancer cell lines. Various strategies for treating cancers with active peptides have been …

[HTML][HTML] Anti-cancer peptides: status and future prospects

G Ghaly, H Tallima, E Dabbish, N Badr ElDin… - Molecules, 2023 - mdpi.com
The dramatic rise in cancer incidence, alongside treatment deficiencies, has elevated
cancer to the second-leading cause of death globally. The increasing morbidity and mortality …

On the selectivity and efficacy of defense peptides with respect to cancer cells

F Harris, SR Dennison, J Singh… - Medicinal research …, 2013 - Wiley Online Library
Here, we review potential determinants of the anticancer efficacy of innate immune peptides
(ACPs) for cancer cells. These determinants include membrane‐based factors, such as …

Anticancer potential of animal venoms and toxins

A Gomes, P Bhattacharjee, R Mishra, AK Biswas… - 2010 - nopr.niscpr.res.in
Anticancer drug development from natural resources are ventured throughout the world.
Animal venoms and toxins a potential bio resource and a therapeutic tool were known to …