Advancements in inner ear development, regeneration, and repair through otic organoids
The vertebrate inner ear contains a diversity of unique cell types arranged in a particularly
complex 3D cytoarchitecture. Both of these features are integral to the proper development …
complex 3D cytoarchitecture. Both of these features are integral to the proper development …
Stem cells as potential therapeutics for hearing loss
Q Fang, Y Wei, Y Zhang, W Cao, L Yan… - Frontiers in …, 2023 - frontiersin.org
Hearing impairment is a global health problem. Stem cell therapy has become a cutting-
edge approach to tissue regeneration. In this review, the recent advances in stem cell …
edge approach to tissue regeneration. In this review, the recent advances in stem cell …
Transcriptional response to mild therapeutic hypothermia in noise-induced cochlear injury
S Rincon Sabatino, R Sangaletti, A Griswold… - Frontiers in …, 2024 - frontiersin.org
Introduction Prevention or treatment for acoustic injury has been met with many translational
challenges, resulting in the absence of FDA-approved interventions. Localized hypothermia …
challenges, resulting in the absence of FDA-approved interventions. Localized hypothermia …
[HTML][HTML] The Role of Pericytes in Inner Ear Disorders: A Comprehensive Review
A Maniaci, M Briglia, F Allia, G Montalbano… - Biology, 2024 - mdpi.com
Simple Summary Hearing disorders, especially deafness, are highly debilitating diseases
that negatively affect the quality of life. Despite the high incidence, the underlying …
that negatively affect the quality of life. Despite the high incidence, the underlying …
Transcriptomic analysis reveals prolonged neurodegeneration in the hippocampus of adult C57BL/6N mouse deafened by noise
SY Lee, HS Lee, MH Park - Frontiers in Neuroscience, 2024 - frontiersin.org
Introduction Several studies have reported a significant correlation between noise-induced
hearing loss and cognitive decline. However, comprehensive analyses of this relationship …
hearing loss and cognitive decline. However, comprehensive analyses of this relationship …
The Protective Effects of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in Noise-Induced Hearing Loss of Rats
SY Kim, JE Lee, SH Kang, SM Lee, J Jeon, DR Lee - Cells, 2022 - mdpi.com
A few prior animal studies have suggested the transplantation or protective effects of
mesenchymal stem cells (MSCs) in noise-induced hearing loss. This study intended to …
mesenchymal stem cells (MSCs) in noise-induced hearing loss. This study intended to …
[HTML][HTML] Physical rehabilitation for sensorineural hearing loss in childhood: Progress and challenges
L Zhang, PJ Huang, X Deng, J Tang, Y Zhai… - World Journal of Clinical …, 2025 - wjgnet.com
Early intervention for sensorineural hearing loss (SNHL) in childhood is crucial for auditory
and language development. In recent years, innovative auditory stimulation techniques and …
and language development. In recent years, innovative auditory stimulation techniques and …
Transdifferentiation of Human Dental Pulp Mesenchymal Stem Cells into Spiral Ganglion-like Neurons
Y MESSAT, marta Martin-Fernandez, S ASSOU… - bioRxiv, 2024 - biorxiv.org
Spiral ganglion neurons (SGN) carry auditory information from sensory hair cells (HCs) to
the brain. These auditory neurons, which are the target neurons of cochlear implants …
the brain. These auditory neurons, which are the target neurons of cochlear implants …
[PDF][PDF] Efficacy and Mechanisms of Mild Therapeutic Hypothermia for Hearing Preservation from Noise-Induced Hearing Loss
S Rincon Sabatino - 2023 - scholarship.miami.edu
Noise-induced hearing loss (NIHL) is an acquired form of sensorineural hearing loss
associated with cochlear trauma in response to acoustic over-stimulation. NIHL may present …
associated with cochlear trauma in response to acoustic over-stimulation. NIHL may present …
Efficacy and Mechanisms of Mild Therapeutic Hypothermia for Hearing Preservation from Noise-Induced Hearing Loss
SR Sabatino - scholarship.miami.edu
Noise-induced hearing loss (NIHL) is an acquired form of sensorineural hearing loss
associated with cochlear trauma in response to acoustic over-stimulation. NIHL may present …
associated with cochlear trauma in response to acoustic over-stimulation. NIHL may present …