Adalimumab, ustekinumab, and secukinumab in the management of hidradenitis suppurativa: a review of the real-life experience

F Martora, M Megna, T Battista, L Potestio… - Clinical, Cosmetic …, 2023 - Taylor & Francis
To date, adalimumab (ADA) is the only biotechnology drug approved for the management of
hidradenitis suppurativa (HS), an inflammatory skin condition. However, it quickly became …

New perspectives on the treatment of hidradenitis suppurativa

V Amat-Samaranch, E Agut-Busquet… - … in Chronic Disease, 2021 - journals.sagepub.com
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by the
presence of painful nodules, abscesses, chronically draining fistulas, and scarring in …

[HTML][HTML] New and emerging targeted therapies for hidradenitis suppurativa

A Markota Čagalj, B Marinović… - International journal of …, 2022 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease deriving
from the hair follicles. The formation of inflammatory nodules, abscesses, fistulas, and sinus …

Biologics for hidradenitis suppurativa: evolution of the treatment paradigm

CA Maronese, C Moltrasio, G Genovese… - Expert Review of …, 2024 - Taylor & Francis
Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …

Guselkumab, risankizumab, and tildrakizumab in the management of hidradenitis suppurativa: a review of existing trials and real-life data

F Martora, M Scalvenzi, T Battista… - Clinical, Cosmetic …, 2023 - Taylor & Francis
The treatment of hidradenitis suppurativa (HS) has always been a real challenge for
dermatologists; to date, the only biologic drugs approved for HS are adalimumab, an anti …

The inflammatory proteome of hidradenitis suppurativa skin is more expansive than that of psoriasis vulgaris

K Navrazhina, S Garcet, JW Frew, X Zheng… - Journal of the American …, 2022 - Elsevier
Background Although hidradenitis suppurativa (HS) shares some transcriptomic and cellular
infiltrate features with psoriasis, their skin proteome remains unknown. Objective To define …

[HTML][HTML] New insight into the molecular pathomechanism and immunomodulatory treatments of hidradenitis suppurativa

E Molinelli, H Gioacchini, C Sapigni… - International Journal of …, 2023 - mdpi.com
Hidradenitis suppurativa (HS) is an immune-mediated inflammatory disorder characterized
by deep-seated nodules, abscesses, sinus tracts and scars localized in the intertriginous …

[HTML][HTML] Short-term effectiveness, safety, and potential predictors of response of secukinumab in patients with severe hidradenitis suppurativa refractory to biologic …

P Fernandez-Crehuet, S Haselgruber… - Dermatology and …, 2023 - Springer
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Biologic
drugs have a key role in the long-term anti-inflammatory treatment of moderate to severe …

[HTML][HTML] Insights into the Pathogenesis of HS and Therapeutical Approaches

E Rosi, MT Fastame, I Scandagli, A Di Cesare… - Biomedicines, 2021 - mdpi.com
Hidradenitis suppurativa (HS) is a debilitating, chronic,(auto) inflammatory disease primarily
affecting apocrine gland-rich areas of the body. Although pathogenic mechanisms …

[HTML][HTML] Emerging treatments and the clinical trial landscape for hidradenitis suppurativa part I: topical and systemic medical therapies

NM Fragoso, R Masson, TJ Gillenwater, VY Shi… - Dermatology and …, 2023 - Springer
Hidradenitis suppurativa (HS) is an oftentimes debilitating condition that presents with
painful nodules, abscesses, and sinus tracts. This condition is challenging to treat, in part …