Endogenous DNA derived from the nuclei or mitochondria is released into the bloodstream
following cell damage or death. Extracellular DNA, called cell-free DNA (cfDNA), is …

Circadian rhythms (Nobel prize for Medicine 2017) regulate, under action of biological
clocks located both at the level of central nervous system and inside peripheral cells, several …

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death due to its
early recurrence and widespread metastatic potential. Accumulating studies have reported …

Rheumatoid arthritis (RA) is an advanced autoimmune disease described by joint
involvement. The special properties of mesenchymal stem cells (MSCs) introduced them as …

Circadian rhythm perturbations can impact the evolution of different conditions, including
autoimmune diseases. This narrative review summarizes the current understanding of …

Lung adenocarcinoma (LUAD) is often diagnosed at an advanced stage, so it is necessary
to identify potential biomarkers for the early diagnosis and prognosis of LUAD. In our study …

Abstract Period circadian clock 2 (PER2) is involved in the pathogenesis of various
inflammatory and autoimmune diseases. However, there are gaps in our understanding of …

Objective Diurnal variation of symptoms are observed in rheumatoid arthritis, especially in
productions of cytokines that show peak concentrations during mid night. In contrast …

Objective To observe and analyze the interaction between excessive mechanical stress
(MS) and decreased sex hormones on Temporomandibular Joint Osteoarthritis (TMJ-OA) …

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic
polyarticular pain, and its main pathological features include inflammatory cell infiltration …