Recent studies have demonstrated the impact of pro-inflammatory signaling and reactive
microglia/macrophages on the formation of Müller glial-derived progenitor cells (MGPCs) in …

Müller glia, as prominent glial cells within the retina, plays a significant role in maintaining
retinal homeostasis in both healthy and diseased states. In lower vertebrates like zebrafish …

The purpose of this study was to investigate how ID factors regulate the ability of Müller glia
(MG) to reprogram into proliferating MG‐derived progenitor cells (MGPCs) in the chick …

Different kinase-dependent cell signaling pathways are known to play important roles in glia-
mediated neuroprotection and reprogramming of Müller glia (MG) into Müller glia-derived …

The purpose of this study was to investigate how ID transcription factors (TFs) regulate the
ability of Müller glia (MG) to reprogram into proliferating MG-derived progenitor cells …

视网膜神经元受损和丢失是视觉系统神经退行性疾病的特征, 可能造成多种致盲性眼病.
利用外源性和内源性干细胞实现向视网膜神经元分化是治疗神经退行性疾病的有效疗法. 然而 …

Ibudilast, an inhibitor of macrophage migration inhibitory factor (MIF) and
phosphodiesterase (PDE), has been recently shown to have neuroprotective effects in a …

Recent studies have demonstrated the complex coordination of pro-inflammatory signaling
and reactive microglia/macrophage on the formation Müller glial-derived progenitor cells …

Background Retinal diseases characterized with irreversible loss of retinal nerve cells, such
as optic atrophy and retinal degeneration, are the main causes of blindness. Current …