Pollution and respiratory disease: can diet or supplements help? A review

T Whyand, JR Hurst, M Beckles, ME Caplin - Respiratory research, 2018 - Springer
Pollution is known to cause and exacerbate a number of chronic respiratory diseases. The
World Health Organisation has placed air pollution as the world's largest environmental …

Diagnosis and treatment of early chronic obstructive lung disease (COPD)

JY Choi, CK Rhee - Journal of clinical medicine, 2020 - mdpi.com
Chronic obstructive lung disease (COPD) is responsible for substantial rates of mortality and
economic burden, and is one of the most important public-health concerns. As the disease …

Estrategias actuales en el manejo de las secreciones traqueobronquiales

A Cortes-Telles, JL Che-Morales… - Neumología y cirugía de …, 2019 - scielo.org.mx
El aumento de la producción de moco es común en pacientes con enfermedades
respiratorias, asimismo, en la población en general como resultado de la exposición a …

Safety of N-Acetylcysteine at High Doses in Chronic Respiratory Diseases: A Review

P Calverley, P Rogliani, A Papi - Drug safety, 2021 - Springer
N-Acetylcysteine (NAC) is widely used in respiratory medicine, with a maximum licensed
dose in chronic use of 600 mg/day; however, some clinical trials have studied the efficacy of …

Weighing the evidence for pharmacological treatment interventions in mild COPD; a narrative perspective

D Singh, AD D'Urzo, JF Donohue, EM Kerwin - Respiratory research, 2019 - Springer
There is increasing focus on understanding the nature of chronic obstructive pulmonary
disease (COPD) during the earlier stages. Mild COPD (Global Initiative for Chronic …

Therapeutic role of N-acetyl cysteine (NAC) for the treatment and/or management of SARS-CoV-2-induced lung damage in hamster model

V Suresh, P Behera, D Parida, AP Mohapatra… - European Journal of …, 2023 - Elsevier
Oxidative stress by reactive oxygen species (ROS) has been hypothesized to be the major
mediator of SARS-CoV-2-induced pathogenesis. During infection, the redox homeostasis of …

Response to intravenous N-acetylcysteine supplementation in critically Ill patients with COVID-19

Y Gamarra-Morales, L Herrera-Quintana… - Nutrients, 2023 - mdpi.com
Administering N-acetylcysteine (NAC) could counteract the effect of free radicals, improving
the clinical evolution of patients admitted to the Intensive Care Unit (ICU). This study aimed …

Influence of n-acetylcysteine maintenance on the pharmacodynamic effects of oral ethanol

WW Stoops, JC Strickland, LR Hays… - Pharmacology …, 2020 - Elsevier
Rationale Glutamate systems play an important role in the abuse related effects of alcohol. n-
Acetylcysteine, a drug that promotes glutamate homeostasis, attenuates a range of alcohol …

A randomized controlled clinical trial in healthy older adults to determine efficacy of glycine and N-acetylcysteine supplementation on glutathione redox status and …

G Lizzo, E Migliavacca, D Lamers, A Frézal… - Frontiers in …, 2022 - frontiersin.org
Glycine and cysteine are non-essential amino acids that are required to generate
glutathione, an intracellular tripeptide that neutralizes reactive oxygen species and prevents …

[HTML][HTML] The effect of carotid chemoreceptor inhibition on exercise tolerance in chronic obstructive pulmonary disease: a randomized-controlled crossover trial

DB Phillips, SÉ Collins, TL Bryan, EYL Wong… - Respiratory …, 2019 - Elsevier
Background Patients with chronic obstructive pulmonary disease (COPD) have an
exaggerated ventilatory response to exercise, contributing to exertional dyspnea and …