Diabetes mellitus, a metabolic disease mainly characterized by hyperglycemia, is becoming
a serious social health problem worldwide with growing prevalence. Many natural …

The heart is imbued with a vast lymphatic network that is responsible for fluid homeostasis
and immune cell trafficking. Disturbances in the forces that regulate microvascular fluid …

Metabolic syndrome (MetS), also known as syndrome X, is a significant risk factor for
cardiovascular disease incidence and mortality. Increasing age, obesity, physical inactivity …

Significance: Atherosclerosis and its complications, such as acute coronary syndromes, are
the leading causes of death worldwide. A wide range of inflammatory processes …

The cerebral microcirculation holds a critical position to match the high metabolic demand
by neuronal activity. Functionally, microcirculation is virtually inseparable from other nervous …

Cerebrovascular atherosclerosis has been identified as a prominent pathological feature of
Alzheimer's disease (AD); the link between vessel pathology and AD risk may also extend to …

Mechanical overload of the vascular wall is a pathological hallmark of life-threatening
abdominal aortic aneurysms (AAA). However, how this mechanical stress resonates at the …

Pericytes are multipotent mesenchymal stromal cells playing an active role in angiogenesis,
vessel stabilisation, maturation, remodelling, blood flow regulation and are able to trans …

Endothelial cells lining blood vessels are essential for maintaining vascular homeostasis
and mediate several pathological and physiological processes. Mechanical stresses …

Commensal microbiota within a holobiont contribute to the overall health of the host via
mutualistic symbiosis. Disturbances in such symbiosis is prominently correlated with a …