Population aging has increased the global prevalence of aging‐related diseases, including
cancer, sarcopenia, neurological disease, arthritis, and heart disease. Understanding aging …

Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders
caused by the interaction of genetic, environmental, and familial factors. These diseases …

Self-assembling peptide-based hydrogels have become a highly attractive scaffold for three-
dimensional (3D) in vitro disease modeling as they provide a way to create tunable matrices …

Alzheimer's disease (AD), the leading cause of dementia, presents a significant global
health challenge with no known cure to date. Central to our understanding of AD …

Abstract Development of biologically relevant and clinically relevant human cerebral cortex
models is demanded by mechanistic studies of human cerebral cortex‐associated …

Peripheral nerve injuries (PNIs) represent a significant challenge in regenerative medicine,
often leading to long-term functional impairments. In this study, we introduce the peripheral …

Brain disorders, encompassing a wide spectrum of neurological and psychiatric conditions,
present a formidable challenge in modern medicine. Despite decades of research, the …

Familial Alzheimer's disease (FAD) is a complex neurodegenerative disorder for which there
are no therapeutics to date. Several mutations in presenilin 1 (PSEN 1), which is the catalytic …

While cardiovascular disease, cancer, and human immunodeficiency virus (HIV) mortality
rates have decreased over the past 20 years, Alzheimer's Disease (AD) deaths have risen …

Abstract Introduction Drug development for Alzheimer's disease has one of the greatest
failure rates of any therapeutic field and AD is still incurable. Glycogen synthase kinase-3β is …