Bacterial infections caused by 'superbugs' are increasing globally, and conventional
antibiotics are becoming less effective against these bacteria, such that we risk entering a …

The growing increase in antibiotic-resistant bacteria has led to the search for new
antibacterial agents capable of overcoming the resistance problem. In recent years …

Antibiotic resistance is a major global health challenge and, worryingly, several key Gram
negative pathogens can become resistant to most currently available antibiotics. Polymyxins …

Klebsiella pneumoniae is a Gram-negative pathogen that has a large accessory genome of
plasmids and chromosomal gene loci. This accessory genome divides K. pneumoniae …

Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Given the spasmodic increment in antimicrobial resistance (AMR), world is on the verge of
“post-antibiotic era”. It is anticipated that current SARS-CoV2 pandemic would worsen the …

The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

In recent years, because of increased resistance to conventional antimicrobials, many
researchers have started to study the synthesis of new antibiotics to control the disease …

Cationic antimicrobial peptides (AMPs) are an intrinsic part of the human innate immune
system. Over 100 different human AMPs are known to exhibit broad-spectrum antibacterial …

The increase in bacterial resistance to one or several antibiotics has become a global health
problem. Recently, nanomaterials have become a tool against multidrug-resistant bacteria …