Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …

The role of polymorphonuclear neutrophils (PMNs) in biology is often recognized during
pathogenesis associated with PMN hyper-or hypo-functionality in various disease states …

Chronic low-grade inflammation has a key role in the aging process, a state called
inflammaging. It is known that the chronic inflammatory condition generates counteracting …

Aberrant glycosylation of tumor cells is recognized as a universal hallmark of cancer
pathogenesis. Overexpression of fucosylated epitopes, such as type I (H1, Lewisa, Lewisb …

Glycans are essential cellular components that facilitate a range of critical functions
important for tissue development and mucosal homeostasis. Furthermore, specific …

The neutrophil, a short-lived effector leukocyte of the innate immune system best known for
its proteases and other degradative cargo, has unique, reciprocal physiological interactions …

Polymorphonuclear neutrophils (PMN s) are innate immune system cells that play an
essential role in eradicating invading pathogens. PMN migration to sites of …

Aberrant glycan epitopes are a classic hallmark of malignant transformation, yet their full
clinical potential in cancer diagnostics and therapeutics is yet to be realized. This is partly …

Simple Summary CD15 (Lewis X) is a typical myeloid antigen presented in myeloid and
monocytic lineages of cells. This molecule interacts with E-, L-and P-selectins, which allows …

Evidence suggests that neutrophils exert specialized effector functions during infection and
inflammation, and that these cells can affect the duration, severity, and outcome of the …