Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Chemical exchange saturation transfer (CEST) and MR Z-spectroscopy in vivo: a review of theoretical approaches and methods

M Zaiss, P Bachert - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Chemical exchange saturation transfer (CEST) of metabolite protons that undergo exchange
processes with the abundant water pool enables a specific contrast for magnetic resonance …

Hyperpolarized Xe NMR signal advancement by metal-organic framework entrapment in aqueous solution

Q Zeng, B Bie, Q Guo, Y Yuan, Q Han… - Proceedings of the …, 2020 - National Acad Sciences
We report hyperpolarized Xe signal advancement by metal-organic framework (MOF)
entrapment (Hyper-SAME) in aqueous solution. The 129Xe NMR signal is drastically …

NMR hyperpolarization techniques for biomedicine

P Nikolaou, BM Goodson… - Chemistry–A European …, 2015 - Wiley Online Library
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

Molecular imaging using a targeted magnetic resonance hyperpolarized biosensor

L Schröder, TJ Lowery, C Hilty, DE Wemmer, A Pines - Science, 2006 - science.org
A magnetic resonance approach is presented that enables high-sensitivity, high-contrast
molecular imaging by exploiting xenon biosensors. These sensors link xenon atoms to …

Cryptophanes and their complexes present and future

T Brotin, JP Dutasta - Chemical reviews, 2009 - ACS Publications
The encapsulation of charged or neutral species in the inner cavity of organic hosts is a
fascinating field of research and represents an important challenge for many research …

MRI of the lungs using hyperpolarized noble gases

HE Möller, XJ Chen, B Saam… - … in Medicine: An …, 2002 - Wiley Online Library
The nuclear spin polarization of the noble gas isotopes 3He and 129Xe can be increased
using optical pumping methods by four to five orders of magnitude. This extraordinary gain …

Simultaneous encapsulation: molecules held at close range

J Rebek Jr - Angewandte Chemie International Edition, 2005 - Wiley Online Library
Reversible encapsulation creates spaces where molecules are temporarily isolated from
others in solution. Molecules are held within the space of the capsule for lifetimes ranging …

Genetically encoded reporters for hyperpolarized xenon magnetic resonance imaging

MG Shapiro, RM Ramirez, LJ Sperling, G Sun, J Sun… - Nature …, 2014 - nature.com
Magnetic resonance imaging (MRI) enables high-resolution non-invasive observation of the
anatomy and function of intact organisms. However, previous MRI reporters of key biological …

Sensitivity enhancement in solution NMR: Emerging ideas and new frontiers

JH Lee, Y Okuno, S Cavagnero - Journal of magnetic resonance, 2014 - Elsevier
Modern NMR spectroscopy has reached an unprecedented level of sophistication in the
determination of biomolecular structure and dynamics at atomic resolution in liquids …