Background: The number of publications on SMAD7 in the field of oncology is increasing
rapidly with an upward tendency. In most cases, the mechanisms of carcinogenesis usually …

Innovative therapeutic strategies in childhood cancer led to a significant reduction in cancer-
related mortality. Cancer survivors are a growing fragile population, at risk of long-term side …

Brief introduction Myocardial infarction (MI) is a common manifestation of certain cardiac
diseases where oxidative stress and fibrosis aggravate the condition markedly. Main …

Imatinib mesylate (IMA) belonging to the selective tyrosine kinase inhibitor family has been
proven to induce cardiotoxic effects along with therapeutic strategies. Nrf2-dependent …

Imatinib Mesylate (IMA) has been widely used to treat with chronic myeloid leukemia (CML).
However, cardiotoxicity associated with IMA is included among the therapeutic strategies …

Imatinib is a classical targeted drug to treat chronic myeloid leukemia (CML). However, it
shows cardiotoxicity, which limits its clinical application. Long noncoding RNA (lncRNA) …

To find novel and effective anti-cancer agents, sixteen novel imamine-1, 3, 5-triazine
derivatives were firstly designed and synthesized using a molecular hybridization strategy …

Purpose 9.4 T magnetic resonance imaging (MRI) has been initially tested on healthy
human volunteers, but its future application will benefit more from experiments with animal …

Hepatic ischemia-reperfusion (I/R) is an important cause of liver damage in many clinical
situations. Toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) is an inflammatory …

Methotrexate (MTX) is an antifolate that is inescapable and widely used to treat autoimmune
diseases and is the gold standard medicine for the arthritic condition. Despite its importance …