Intrinsic optical signal (IOS) imaging promises to be a noninvasive method for high-
resolution examination of retinal physiology, which can advance the study and diagnosis of …

Age-related macular degeneration (AMD) is the leading cause of severe vision loss and
legal blindness. It is known that retinal photoreceptors are the primary target of AMD …

Despite a number of books on biophotonics imaging for medical diagnostics and therapy,
the field still lacks a comprehensive imaging book that describes state-of-the-art …

High resolution microscopy is essential for advanced study of biological structures and
accurate diagnosis of medical diseases. The spatial resolution of conventional microscopes …

Transient retinal phototropism (TRP) has been predominantly observed in rod
photoreceptors activated by oblique visible light stimulation. Dynamic confocal microscopy …

Intrinsic optical signal (IOS) imaging promises a noninvasive method for advanced study
and diagnosis of eye diseases. Before pursuing clinical applications, it is essential to …

Purpose.: The purposes of this study were to investigate the physiological mechanism of
stimulus-evoked fast intrinsic optical signals (IOSs) recorded in dynamic confocal imaging of …

Rod-dominated transient retinal phototropism (TRP) has been recently observed in freshly
isolated mouse and frog retinas. Comparative confocal microscopy and optical coherence …

Functional measurement is important for retinal study and disease diagnosis. Transient
intrinsic optical signal (IOS) response, tightly correlated with functional stimulation, has been …

Quantitative imaging of biomedical specimens is essential in biomedical study and
diagnosis. Given excellent capability in three-dimensional (3D) imaging, optical coherence …