One of the most important issues facing cartilage tissue engineering is the inability to move
technologies into the clinic. Despite the multitude of current research in the field, it is known …

Hyaline cartilage is the nonlinear, inhomogeneous, anisotropic, poro-viscoelastic connective
tissue that serves as friction-reducing and load-bearing cushion in synovial joints and is vital …

One of the challenges of bioprinting is to identify bioinks which support cell growth, tissue
maturation, and ultimately the formation of functional grafts for use in regenerative medicine …

With the advantages of high throughput, digital control, and highly accurate placement of
cells and biomaterial scaffold to the desired 2D and 3D locations, bioprinting has great …

In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-
related stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM …

The articular cartilage has insufficient intrinsic healing abilities, and articular cartilage
injuries often progress to osteoarthritis. Alginate-based scaffolds are attractive biomaterials …

Background Articular cartilage displays a poor repair capacity. The aim of cell-based
therapies for cartilage defects is to repair damaged joint surfaces with a functional …

Cell-based therapy represents a promising treatment strategy for cartilage defects. Alone or
in combination with scaffolds/biological signals, these strategies open many new avenues …

Trauma and disease of bones and joints, frequently involving structural damage to both the
articular cartilage surface and the subchondral bone, result in severe pain and disability for …

Nanofibrous materials, by virtue of their morphological similarities to natural extracellular
matrix, have been considered as candidate scaffolds for cell delivery in tissue‐engineering …