Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia

PJ Pussinen, E Kopra, M Pietiäinen… - Periodontology …, 2022 - Wiley Online Library
Lipopolysaccharide is a virulence factor of gram‐negative bacteria with a crucial importance
to the bacterial surface integrity. From the host's perspective, lipopolysaccharide plays a role …

Diagnostic accuracy of oral fluids biomarker profile to determine the current and future status of periodontal and peri-implant diseases

SS Gul, AA Abdulkareem, AM Sha, A Rawlinson - Diagnostics, 2020 - mdpi.com
Severe periodontitis is ranked as the sixth most prevalent disease affecting humankind, with
an estimated 740 million people affected worldwide. The diagnosis of periodontal diseases …

“Do it yourself” protocol to fabricate dual-detection paper-based analytical device for salivary biomarker analysis

LR Sousa, HA Silva-Neto, LF Castro… - Analytical and …, 2023 - Springer
This paper describes the design and construction of dual microfluidic paper–based
analytical devices (dual-μPADs) as a lab-on-paper platform involving a “do-it-yourself” …

Active matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) in the COVID-19 pandemic

T Sorsa, V Sahni, N Buduneli, S Gupta… - Expert Review of …, 2021 - Taylor & Francis
Introduction Active matrix metalloproteinase (aMMP)-8 utilized in point-of-care testing
(POCT) is regarded as a potential biomarker for periodontal and peri-implant diseases …

Antibody response to oral biofilm is a biomarker for acute coronary syndrome in periodontal disease

M Jaago, N Pupina, A Rähni, A Pihlak… - Communications …, 2022 - nature.com
Cumulative evidence over the last decades have supported the role of gum infections as a
risk for future major cardiovascular events. The precise mechanism connecting coronary …

Elevated baseline salivary protease activity may predict the steadiness of gingival inflammation during periodontal healing: A 12-week follow-up study on adults

UK Gürsoy, D Fteita, FJ Bikker, MA Grande, K Nazmi… - Pathogens, 2020 - mdpi.com
Aim was to profile salivary total protease, Porphyromonas gingivalis gingipain, and
neutrophil elastase activities in relation to the resolution of periodontal inflammation, salivary …

Total fecal IgA levels increase and natural IgM antibodies decrease after gastric bypass surgery

N Istomin, MA Härma, R Akhi, AE Nissinen… - Apmis, 2022 - Wiley Online Library
Obesity is associated with low‐grade inflammation and increased systemic oxidative stress.
Roux‐en‐Y gastric bypass (RYGB) surgery is known to ameliorate the obesity‐induced …

Chronic periodontitis induces the proliferation of pancreatic β‐cells to cause hyperinsulinemia in a rat model

L Ye, Y Lv, Q Wu, Y Chen, X Zhang… - Journal of Periodontal …, 2023 - Wiley Online Library
Abstract Background and Objective The purpose of this study was to determine if chronic
periodontitis (CP) may induce hyperinsulinemia and may have the effect of on pancreatic β …

Advances in periodontal biomarkers.

UK Gürsoy, M Gürsoy - Advances in Clinical Chemistry, 2024 - europepmc.org
Due to technologic advancements, periodontology has witnessed a boost in biomarker
research over the past three decades. Indeed, with the aid of omics, our understanding of …

[PDF][PDF] Detection of bacterial species associated with periodontal disease in a group of patients

C Vodiță, DL Ghergic, EA Vodiță… - Romanian …, 2021 - pdfs.semanticscholar.org
Objectives. The study aimed to detect the presence/quantification of the 12 bacterial strains
more frequently involved in the occurrence and aggravation of periodontal disease in a …