Vector biology meets disease control: using basic research to fight vector-borne diseases
WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …
Advances and opportunities in malaria population genomics
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
[HTML][HTML] A CRISPR–Cas9 gene drive targeting doublesex causes complete population suppression in caged Anopheles gambiae mosquitoes
In the human malaria vector Anopheles gambiae, the gene doublesex (Agdsx) encodes two
alternatively spliced transcripts, dsx-female (AgdsxF) and dsx-male (AgdsxM), that control …
alternatively spliced transcripts, dsx-female (AgdsxF) and dsx-male (AgdsxM), that control …
Improved reference genome of Aedes aegypti informs arbovirus vector control
Female Aedes aegypti mosquitoes infect more than 400 million people each year with
dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress …
dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress …
Phylosymbiosis: relationships and functional effects of microbial communities across host evolutionary history
Phylosymbiosis was recently proposed to describe the eco-evolutionary pattern, whereby
the ecological relatedness of host-associated microbial communities parallels the phylogeny …
the ecological relatedness of host-associated microbial communities parallels the phylogeny …
[HTML][HTML] Diversity and evolution of the P450 family in arthropods
The P450 family (CYP genes) of arthropods encodes diverse enzymes involved in the
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
RD Mesquita, RJ Vionette-Amaral… - Proceedings of the …, 2015 - National Acad Sciences
Rhodnius prolixus not only has served as a model organism for the study of insect
physiology, but also is a major vector of Chagas disease, an illness that affects …
physiology, but also is a major vector of Chagas disease, an illness that affects …
The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito
Gene drives have enormous potential for the control of insect populations of medical and
agricultural relevance. By preferentially biasing their own inheritance, gene drives can …
agricultural relevance. By preferentially biasing their own inheritance, gene drives can …
malERA: an updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …
overwhelming health, equity, and economic benefits. WHO and countries are setting …
Extensive introgression in a malaria vector species complex revealed by phylogenomics
Introduction The notion that species boundaries can be porous to introgression is
increasingly accepted. Yet the broader role of introgression in evolution remains contentious …
increasingly accepted. Yet the broader role of introgression in evolution remains contentious …