Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease whereby
excessive deposition of extracellular matrix proteins (ECM) ultimately leads to respiratory …

The incidence of asthma is a global health problem and requires studies aimed for the
development of new treatments to improve its clinical management, reducing personal and …

Animal models of asthma have shown that limonene, a naturally occurring terpene in citrus
fruits, can reduce inflammation and airway reactivity. However, the mechanism of these …

Asthma remains a significant global health challenge. While both the incidence and mortality
rates have shown a decline, older individuals with asthma exhibit not just more severe …

Angiotensin II (Ang II) is the most dominant effector component of the renin-angiotensin
system (RAS) that generally acts through binding to two main classes of G protein–coupled …

Renin-angiotensin system (RAS) plays an indispensable role in regulating blood pressure
through its effects on fluid and electrolyte balance. As an aside, cumulative evidence from …

Fibrosis is a key feature of chronic lung diseases and occurs as a consequence of aberrant
wound healing. TGFβ1 plays a major role in promoting fibrosis and is the primary target of …

Rheumatoid arthritis (RA) is an autoimmune inflammatory bone destructive disorder that is
orchestrated by multiple systems in the body, including Renin-Angiotensin System (RAS) …

高血压和支气管哮喘分别是心血管系统和呼吸系统常见的慢性病. 基因易感性,
炎症机制以及不良生活方式等均可增加高血压和哮喘的发病风险. 近年来高血压合并哮喘在发病 …

The renin-angiotensin system (RAS) is an intricate endocrine cascade that elicits diverse
biological functions. Angiotensin II (Ang II), as a central component of the RAS, mediates …