A pan-cancer dye for solid-tumour screening, resection and wound monitoring via short-wave and near-infrared fluorescence imaging

BE Mc Larney, AY Sonay, E Apfelbaum… - Nature Biomedical …, 2024 - nature.com
The efficacy of fluorescence-guided surgery in facilitating the real-time delineation of
tumours depends on the optical contrast of tumour tissue over healthy tissue. Here we show …

Aiming the magic bullet: targeted delivery of imaging and therapeutic agents to solid tumors by pHLIP peptides

YK Reshetnyak, OA Andreev… - Frontiers in …, 2024 - frontiersin.org
The family of pH (Low) Insertion Peptides (pHLIP) comprises a tumor-agnostic technology
that uses the low pH (or high acidity) at the surfaces of cells within the tumor …

[HTML][HTML] A pan-cancer agent for screening, resection and wound monitoring via NIR and SWIR imaging

B Mc Larney, A Sonay, E Apfelbaum, N Mostafa… - Research …, 2024 - ncbi.nlm.nih.gov
Fluorescence guided surgery (FGS) facilitates real time tumor delineation and is being
rapidly established clinically. FGS efficacy is tied to the utilized dye and provided tumor …

Tracking the Fate of Therapeutic Proteins Using Ratiometric Imaging of Responsive Shortwave Infrared Probes

P Shrestha, N Patel, J Kalen, S Usama, M Schnermann - 2024 - chemrxiv.org
Monoclonal antibodies (mAbs) are essential agents for cancer treatment and diagnosis.
Advanced optical imaging strategies have the potential to address specific questions …

Tissue‐seeking dyes for in vivo applications

Y Ma, C Qin, Y Lei, X Yang, Z Lei - Smart Molecules - Wiley Online Library
In vivo optical imaging has become an invaluable tool for visualizing and monitoring
biological processes in living organisms. A key component of these imaging techniques is …

A pan-cancer agent for screening, resection and wound monitoring via NIR and SWIR imaging

J Grimm, B Mc Larney, A Sonay, E Apfelbaum… - 2024 - researchsquare.com
Fluorescence guided surgery (FGS) facilitates real time tumor delineation and is being
rapidly established clinically. FGS efficacy is tied to the utilized dye and provided tumor …