Gardnerella Revisited: Species Heterogeneity, Virulence Factors, Mucosal Immune Responses, and Contributions to Bacterial Vaginosis
E Shvartsman, JE Hill, P Sandstrom… - Infection and …, 2023 - Am Soc Microbiol
Gardnerella species are associated with bacterial vaginosis (BV) and have been
investigated as etiological agents of the condition. Nonetheless, the isolation of this taxon …
investigated as etiological agents of the condition. Nonetheless, the isolation of this taxon …
[HTML][HTML] The role of sialidases in the pathogenesis of bacterial vaginosis and their use as a promising pharmacological target in bacterial vaginosis
L Chen, J Li, B Xiao - Frontiers in Cellular and Infection Microbiology, 2024 - frontiersin.org
Bacterial vaginosis (BV) is an infection of the genital tract characterized by disturbance of the
normally Lactobacilli-dominated vaginal flora due to the overgrowth of Gardnerella and …
normally Lactobacilli-dominated vaginal flora due to the overgrowth of Gardnerella and …
[HTML][HTML] Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips
Z Izadifar, J Cotton, S Chen, V Horvath… - Nature …, 2024 - nature.com
Modulation of the cervix by steroid hormones and commensal microbiome play a central role
in the health of the female reproductive tract. Here we describe organ-on-a-chip (Organ …
in the health of the female reproductive tract. Here we describe organ-on-a-chip (Organ …
Prevotella are major contributors of sialidases in the human vaginal microbiome.
P Pelayo, FA Hussain, CA Werlang, C Wu… - bioRxiv, 2024 - biorxiv.org
Elevated bacterial sialidase activity in the female genital tract is strongly associated with
poor health outcomes including preterm birth and bacterial vaginosis. These negative effects …
poor health outcomes including preterm birth and bacterial vaginosis. These negative effects …