The humoral immune landscape in Parkinson's disease: Unraveling antibody and B cell changes

Z Baridjavadi, M Mahmoudi, N Abdollahi… - Cell Biochemistry …, 2024 - Wiley Online Library
Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by the
accumulation of α‐synuclein (α‐syn) in the brain and progressive loss of dopaminergic …

[HTML][HTML] Genetic variation and pesticide exposure influence blood DNA methylation signatures in females with early-stage Parkinson's disease

SL Schaffner, W Casazza, F Artaud, C Konwar… - npj Parkinson's …, 2024 - nature.com
Although sex, genetics, and exposures can individually influence risk for sporadic
Parkinson's disease (PD), the joint contributions of these factors to the epigenetic etiology of …

Alterations of Peripheral Lymphocyte Subsets in Isolated Rapid Eye Movement Sleep Behavior Disorder

Y Zheng, Y Li, H Cai, W Kou, C Yang, S Li… - Movement …, 2024 - Wiley Online Library
Background Adaptive immune dysfunction may play a crucial role in Parkinson's disease
(PD) development. Isolated rapid eye movement sleep behavior disorder (iRBD) represents …

Activation of central cannabinoid type 2 receptors, but not on peripheral immune cells, is required for endocannabinoid-mediated neuroprotection in Parkinson´ s …

L Ayerra, MA Abellanas, C Vidaurre, L Basurco… - 2024 - researchsquare.com
Background Neuroinflammation is a key feature of Parkinsons disease (PD), a
neurodegenerative disease for which there is no cure. The cannabinoid receptor type 2 …